by Pennington Biomedical Research Center A new study offers the first evidence that a protein named BAM15 acts as an energy uncoupler and could be an effective drug for treating obesity and related diseases. Obesity affects more than 650 million people worldwide and drives a number of dangerous health conditions, including type 2 diabetes, heart...
Small and minimally invasive ‘Detachable Microneedle Depots’ effectively deliver stem cells for localized MSC therapy of skin disorders Credit: Khademhosseini Lab (LOS ANGELES) — Mesenchymal stem cells (MSCs) are multipotent in that they naturally replenish the cell types that build our bone, cartilage and adipose tissues. However, their much broader regenerative potential, based on their...
Chemical compound restores tetracycline’s effectiveness by blocking bacterial resistance. The latest generation of tetracyclines — a class of powerful, first-line antibiotics — was designed to thwart the two most common ways bacteria resist such drugs. But a new study from researchers at Washington University in St. Louis and the National Institutes of Health (NIH) has...
Researchers at the Terasaki Institute enhance tool for extraction of samples used in monitoring patient health (LOS ANGELES) – The interstitial fluid is a major component of the liquid environment in the body and fills the spaces between the body’s cells. In contrast, blood circulates only within the circulatory vessels of the body and is...
by University of Utah When things get rough, many Americans turn to prescription pills. About one in eight over the age of 12 take antidepressants for mental disorders such as depression and anxiety, and a quarter of those have done so for 10 years or more, according to a 2017 study by the National Center...
by McMaster University McMaster University researchers have discovered a combination punch to treat drug-resistant infections that is showing promise based on testing in mice. Researchers found that a natural product called dephostatin is an effective partner for the antibiotic colistin in treating infections caused by the bacteria Salmonella. Colistin is considered a last-resort antibiotic for...
Frequently, promising cancer therapies fail when applied to patients in the real clinical setting. This occurs despite many of these new treatments demonstrating promising results at the preclinical stage in the lab. One explanation is that many of the tumor models used in early research phases are established cell lines that have been growing for...
CREDIT: DR MANEL ESTELLER Scientists have used 3D models to break down the DNA behavior of cancer cells, in a breakthrough new study which could revolutionize treatment for the disease. In what is a first for science, a research team led by Dr Manel Esteller, Director of the Josep Carreras Leukaemia Research Institute (IJC), demonstrated...
As interest in the application of plasma medicine — the use of low-temperature plasma (LTP) created by an electrical discharge to address medical problems — continues to grow, so does the need for research advancements proving its capabilities and potential impacts on the health care industry. Across the world, many research groups are investigating plasma...
University of Virginia’s School of Medicine and School of Engineering, is using focused soundwaves to overcome the natural ‘blood-brain barrier,’ which protects the brain from harmful pathogens. Credit: Dan Addison | UVA Communications University of Virginia researchers are pioneering the use of focused ultrasound to defy the brain’s protective barrier so that doctors could, at...
