by Bob Yirka, Medical Xpress (A) Schematic of the device geometry illustrating the bubble breakup mechanism. (B) Three-dimensional optical profilometry measurement of the SU-8 mold used to fabricate the microdevices. (C–F) Optical micrographs of the nanospraying process. As the liquid and gas phases enter the junction nozzle, the liquid phase focuses the gas into a...
Chemists tend to think of the human body as operating out of a sense-and-respond paradigm. For example, you eat sugar, the pancreas senses the intake, and it responds by releasing the hormone insulin to keep your glucose levels in check. Scientists have long wondered whether there is a similar regulatory strategy for clearing other metabolites, like amino...
IMAGE: IN THE BRAIN OF THE TRANSGENIC MOUSE, TWO NERVE CELLS GLOW RED BECAUSE THEY HAVE ABSORBED MEMBRANE VESICLES CONTAINING FUNCTIONAL PROTEIN FROM INTESTINAL BACTERIA. BLUE: NUCLEI OF THE OTHER CELLS IN THE BRAIN TISSUE. CREDIT: STEFAN MOMMA, GOETHE UNIVERSITY FRANKFURT, GERMANY FRANKFURT. In the human body, bacteria are in the majority: According to estimates,...
by University of Helsinki Figure 1. Manhattan and QQ plots of genome‐wide association study (GWAS) results combined in fixed‐effects meta‐analysis. We performed a GWAS of endotoxemia, measured by limulus amebocyte lysate assay in 11 296 individuals with Finnish ancestry. The horizontal red line represents genome‐wide significance (P<5×10−8). Single‐nucleotide polymorphisms in 5 independent loci available in all cohorts...
by University of Pennsylvania Credit: CC0 Public Domain Immune cells called “killer T cells,” also known as cytotoxic or cytolytic CD8 T cells, normally stay in the bloodstream and do not enter organs and other tissues, according to a new study from scientists in the Perelman School of Medicine at the University of Pennsylvania. The discovery,...
PROF. DR. RER. NAT. STEPHANIE GANAL-VONARBURG DEPARTMENT FOR BIOMEDICAL RESEARCH (DBMR), UNIVERSITY OF BERN, AND UNIVERSITY CLINIC OF VISCERAL SURGERY AND MEDICINE OF THE INSELSPITAL, UNIVERSITY HOSPITAL BERN view more CREDIT: COURTESY OF STEPHANIE GANAL-VONARBURG B cells are white blood cells that develop to produce antibodies. These antibodies, or immunoglobulins, can bind to harmful foreign...
Analysis of particles shed by tumors points to new, less invasive way to diagnose malignancies CEDARS-SINAI MEDICAL CENTER MAGNIFIED IMAGE SHOWS PROSTATE CANCER CELLS EXHIBITING FORMATION OF EXTRACELLULAR VESICLES ON THE CELL MEMBRANES, WHICH CONTAIN TUMOR-DERIVED PROTEINS AND ARE IMPLICATED IN THE SPREAD OF CANCER. view more CREDIT: IMAGE BY CEDARS-SINAI. A new study sheds...
A new study reveals that the common asthma drug salbutamol may offer potential as a treatment for Alzheimer’s disease LANCASTER UNIVERSITY A new study reveals that the common asthma drug salbutamol may offer potential as a treatment for Alzheimer’s disease. Alzheimer’s disease is the most common form of dementia, affecting 47 million people worldwide and...
Experiments in mice have shown early success in vaccinating them against potentially deadly bacterial infections, such as methicillin-resistant Staphylococcal aureus, or MRSA, the strain resistant to most drug treatments. The new vaccination strategy, developed by researchers at NYU Grossman School of Medicine, targets toxic molecules released by all Staphylococcal bacteria, called leukocidins, rather than directly...
by The Scripps Research Institute Scientists at Scripps Research have developed molecules that can remodel the bacterial population of intestines to a healthier state and they have shown—through experiments in mice—that this reduces cholesterol levels and strongly inhibits the thickened-artery condition known as atherosclerosis. The scientists, who report their findings in Nature Biotechnology, created a...
