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Regenerative drug restores bone in preclinical study
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Regenerative drug restores bone in preclinical study

by Main Line Health  Degeneration of the mouse jawbone in the presence of ligature followed by regeneration of the jawbone post-ligature and post-drug. (Aab) The ligature-induced periodontitis model. 5–0 silk suture was passed through the interdentium between the maxillary first molar, the second molar and third molar using Dumont forceps. Suture was tied firmly using...

Dissemination of bone metastasis linked with bone remodeling
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Dissemination of bone metastasis linked with bone remodeling

by Baylor College of Medicine Credit: Pixabay/CC0 Public Domain Years to decades after breast tumors have been removed, cancer may return or metastasize in other organs. Bone is frequently affected by metastasis and in the current study published in the journal Cancer Discovery, a team led by researchers at Baylor College of Medicine shows in an...

UArizona researchers develop ultra-thin ‘computer on the bone’
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UArizona researchers develop ultra-thin ‘computer on the bone’

UNIVERSITY OF ARIZONA COLLEGE OF ENGINEERING IMAGE: OSSEOSURFACE ELECTRONIC DEVICES, WHICH ATTACH DIRECTLY TO THE BONE, COULD ONE DAY HELP PHYSICIANS MONITOR BONE HEALTH. ONE IS SHOW HERE APPLIED TO A SYNTHETIC BONE IN THE GUTRUF LAB AT THE UNIVERSITY OF ARIZONA. CREDIT: GUTRUF LAB A team of University of Arizona researchers has developed an...

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Keeping bone in its place

by Anivarya Kumar, Vanderbilt University Heterotopic ossification (HO) is the formation of bone within soft tissue such as muscle, leading to pain and potentially the inability to use a limb. Once thought to be primarily a genetic disease, the cause of most trauma-induced HO is unknown. Reporting this month in the journal Calcified Tissue International, Jonathan Schoenecker, MD,...

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AAOS: supplement use low in patients with osteoporosis, hip fracture

(HealthDay)—Of patients diagnosed with osteoporosis who have a history of hip fracture, only 14 percent are receiving appropriate calcium and vitamin D supplementation, according to a study presented at the annual meeting of the American Academy of Orthopaedic Surgeons, held from March 12 to 16 in Las Vegas. Evan D. Nigh, of the University of...

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Osteoporosis breakthrough: Bone mass increased by 800 percent

A groundbreaking set of studies has found that blocking certain receptors in the brain leads to the growth of remarkably strong bones. Could a new osteoporosis treatment be on the horizon? Primarily a disease of old age, osteoporosis can cause bones to become gradually weaker. Image: Osteoporosis most commonly affects older women. Over time, bones become so porous that minor...

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Small molecule plays big role in weaker bones as we age

MEDICAL COLLEGE OF GEORGIA AT AUGUSTA UNIVERSITY AUGUSTA, Ga. (Sept. 18, 2018) – With age, expression of a small molecule that can silence others goes way up while a key signaling molecule that helps stem cells make healthy bone goes down, scientists report. They have the first evidence in both mouse and human mesenchymal stem...

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Chip-based blood test for multiple myeloma could make bone biopsies a relic of the past

IMAGE: A NEW UNIVERSITY OF KANSAS RESEARCH EFFORT FEATURED IN THE CURRENT EDITION OF INTEGRATIVE BIOLOGY HAS RESULTED IN A LOW-COST, RELIABLE BLOOD TEST THAT USES A SMALL PLASTIC CHIP ABOUT LAWRENCE — The diagnosis and treatment of multiple myeloma, a cancer affecting plasma cells, traditionally forces patients to suffer through a painful bone biopsy. During...