September 2, 2024 by Walter and Eliza Hall Institute of Medical Research Chimeric antigen receptor (CAR) T cells, genetically engineered leukocytes (white blood cells), in their fight against glioblastoma, a deadly type of glioma. Credit: Journal for ImmunoTherapy of Cancer (2024). DOI: 10.1136/jitc-2024-009486Researchers at WEHI have identified a promising new two-in-one treatment that not only...
September 4, 2024 by Robin Foster In news that should reassure folks glued to their cellphones all day, a new international review finds no link between cellphone use and brain cancer. Commissioned by the World Health Organization (WHO), the review included 11 experts from 10 countries who sifted through decades of research—5,000 studies published between...
by Lauran Neergaard This combination of MRI scan images provided by the New England Journal of Medicine in March 2024 shows the progress of a glioblastoma patient who received CAR-T therapy which uses modified versions of T cells from a patient’s own immune system. Studies published by the New England Journal of Medicine on Wednesday,...
by Institute of Cancer Research Mechanism of action of 2-OHOA. (1) 2-OHOA regulates the cell membrane composition by both direct incorporation into the lipid bilayer and regulation of important lipid metabolism enzymes. (2) Among other structural effects on the lipid bilayer, these changes in lipid composition regulate the raft-to-nonraft lipid balance, which causes translocation of numerous...
University of Sussex led research identifies protein (PANK4) as an obstacle that blocks cancer cells from responding to chemotherapeutic treatment for glioblastomaPeer-Reviewed Publication UNIVERSITY OF SUSSEX New research by the University of Sussex could help to increase life expectancy and improve treatment for an aggressive brain cancer, which impacts thousands of people every year in...
By Paul McClure November 05, 2023Researchers have found that a Parkinson’s drug can be repurposed to treat metastatic breast cancer and brain metastasesDepositphotos Researchers have found that a now-discontinued drug used to treat the symptoms of Parkinson’s disease may be effective at treating metastatic breast cancer and the brain metastases that can often result. The repurposed...
by Flinders University Glioblastoma (histology slide). Credit: Wikipedia/CC BY-SA 3.0A new study shows that cerebrospinal fluid reduces current treatment efficacy in brain cancer and identifies new therapeutic opportunities. Cerebrospinal fluid, the clear colorless liquid that protects the brain, also may be a factor that makes brain cancers resistant to treatment, Australian researchers led by Associate Professor...
by Will Sansom, University of Texas Health Science Center at San Antonio Credit: Pixabay/CC0 Public Domain The Mays Cancer Center at The University of Texas Health Science Center at San Antonio recently conducted a clinical trial combining two drugs in patients with recurrent, high-grade glioblastoma (GBM). The Mays Cancer Center, one of the four National Cancer...
by Spectrum Health Prakash Chinnaiyan, M.D., a physician scientist in the Department of Radiation Oncology at Corewell Health in Southeast, Mich. Credit: Elizabeth Debeliso, Corewell Health For decades, researchers have marveled at the ability of glioblastoma, a particularly aggressive brain cancer, to turn off a patient’s cancer-fighting immune cells, thereby allowing tumors to grow freely. This remains...
by Melissa Rohman, Northwestern University Credit: Pixabay/CC0 Public Domain Repeat radiation therapy combined with the monoclonal antibody drug bevacizumab extended progression-free survival in patients with recurrent glioblastoma, according to findings from a recent clinical trial published in the Journal of Clinical Oncology. Jeffrey Raizer, MD, adjunct professor in the Ken and Ruth Davee Department of Neurology’s Division...
