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Discovery illuminates how Parkinson’s disease spreads in the brain
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Discovery illuminates how Parkinson’s disease spreads in the brain

by  Weill Cornell Medical College Weill Cornell Medicine. Credit: Sharma Lab Aggregates of the protein alpha-synuclein spread in the brains of people with Parkinson’s disease through a cellular waste-ejection process, suggests a new study led by Weill Cornell Medicine researchers. During the process, called lysosomal exocytosis, neurons eject protein waste they cannot break down and recycle....

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How the brain develops: a new way to shed light on cognition

A new study introduces a new neurocomputational model of the human brain that could shed light on how the brain develops complex cognitive abilities and advance neural artificial intelligence research. The study was carried out by an international group of researchers from the Institut Pasteur and Sorbonne Université in Paris, the CHU Sainte-Justine, Mila –...

How fear memories get stuck in some brains
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How fear memories get stuck in some brains

by Linköping University Credit: Pixabay/CC0 Public Domain Researchers at Linköping University, Sweden, have discovered a biological mechanism that increases the strength with which fear memories are stored in the brain. The study, carried out in rats, is published in Molecular Psychiatry. It provides new knowledge on the mechanisms behind anxiety-related disorders, and identifies shared mechanisms behind...

Researchers test hybrid, soft/hard nanocarriers to deliver drugs to the brain
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Researchers test hybrid, soft/hard nanocarriers to deliver drugs to the brain

IOWA STATE UNIVERSITY IMAGE: IOWA STATE UNIVERSITY AND NANOVACCINE INSTITUTE RESEARCHERS, LEFT TO RIGHT, ANWESHA SARKAR, RIZIA BARDHAN AND DONALD SAKAGUCHI ARE WORKING TO CREATE NANOCARRIERS THAT DELIVER DRUGS ACROSS THE BLOOD BRAIN BARRIER. CREDIT: PHOTO BY CHRISTOPHER GANNON/IOWA STATE UNIVERSITY. AMES, Iowa – Rizia Bardhan made a fist with one hand then covered it...

Locating a switch to tell the brain when to learn and when to remember
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Locating a switch to tell the brain when to learn and when to remember

by Pasteur Institute Virtual reality environment seen by mice. Credit: Ruy Gómez-Ocádiz, Christoph Schmidt-Hieber, Institut Pasteur The memory system alternates between periods of learning and remembering. These two functions are controlled by different neural circuits. Using an animal model, scientists from the Institut Pasteur recently identified a neural signal in the hippocampus, a brain region...

The brain can detect infection with malaria
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The brain can detect infection with malaria

by Instituto Gulbenkian de Ciência (IGC)  Brain vascular endothelial cells (blue) internalize particles released by erythrocytes infected with the malaria parasite (pink and red). Credit: Teresa Pais, 2022 A team of researchers from the Instituto Gulbenkian de Ciência (IGC) revealed that cells of the brain can detect the presence of malaria parasites in the blood,...

Study reveals fentanyl’s effects on the brain
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Study reveals fentanyl’s effects on the brain

by Massachusetts General Hospital Credit: Unsplash/CC0 Public Domain Fentanyl is used to supplement sedation and to relieve severe pain during and after surgery, but it’s also one of the deadliest drugs of the opioid epidemic. In research conducted by investigators at Massachusetts General Hospital (MGH) and published in PNAS Nexus, tests of the brain’s electrical activity revealed...

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Day or night — your brain is always listening

You’re fast asleep. But your brain isn’t taking the night off, according to new research funded by the U.S. National Science Foundation. Researchers studied activity in the human cerebral cortex in response to music and other sounds. They observed vigorous auditory responses in the sleeping brain, similar in many ways to responses in the wakeful state but...

Potential way to tune the brain into learning mode
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Potential way to tune the brain into learning mode

by University of Manchester Credit: Pixabay/CC0 Public Domain A study by University of Manchester neuroscientists into the effect of surprise on our memory has inadvertently discovered a method which might help us to perform better in exams. In the study, published in the Journal of Neuroscience, 26 people were shown pictures of objects that were either...