Medscape Medical News Megan Brooks August 14, 2024 BRCA1 and BRCA2 pathogenic variants carry well-known associations with breast and ovarian cancers in women, which has led to robust clinical guidelines for early genetic testing and risk-reduction strategies. Male carriers of BRCA1/2 pathogenic variants also face an increased risk for cancer, particularly of the prostate, pancreas,...
Tag: <span>BRCA mutations</span>
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For people with certain BRCA mutations, activating the immune system could be promising treatment
MEMORIAL SLOAN KETTERING CANCER CENTER Treatments that harness the immune system to fight cancer have greatly improved outcomes for some people with cancer. Scientists are learning more about why some people respond much better than others to these drugs. One major factor is something called tumor mutation burden (TMB) — the number of DNA changes...