Tag: <span>cancer-causing fusions</span>

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Tool targets cancer-causing fusions’ weak spot

by St. Jude Children’s Research Hospital Model of fusion etiology and study design. a Theoretical mechanisms of oncogenic fusion formation. Scenario 1: the DNA breakpoints (red lines) can lead to the fusion of coding exons (thick boxes) from N’ gene to 5’ untranslated region (UTR; thin boxes) of C’ gene and result in the conversion of the...