by Weill Cornell Medical College Perhexiline maleate induces cell death of human pancreatic cancer organoids. (Red: Cell death marker; Blue: DAPI). Credit: Xiaohua DuanA drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell...
PUBLISHED TUE, AUG 15 2023 9:37 AM EDT YouTube on Tuesday announced a new policy for combatting medical misinformation on the video-sharing platform. The company will remove content that contradicts well-established guidance from health officials about topics like Covid-19, reproductive health, cancer and harmful substances, among others. YouTube said it will determine whether a condition...
Tiny “dots” transform light, enabling big advancements UNIVERSITY OF CALIFORNIA – RIVERSIDE IMAGE: NEW MATERIAL COULD IMPRO A new material, created at the little-explored intersection of organic and inorganic chemistry, could not only enable more powerful solar panels, but it could also usher in the next generation of cancer treatments. Described in a Nature Chemistry journal paper published today,...
by Thamarasee Jeewandara, Medical Xpress Design of IL2-ep13nsEV and its utilization in treating breast cancer. To generate this active immunotherapy, the sEVs from autologous DCs are engineered with surface membrane–bound IL2 by expressing IL2-MFG-E8. This personalization of DC-derived sEV (p13nsEV) is achieved by loading lysed surgically harvested breast cancer cells onto engineered autologous DCs followed...
PUBLISHED SAT, FEB 11 202310:00 AM EST Ashley Capoot@ASHLEYCAPOOTSHARE Radioligand therapy, a targeted form of cancer treatment, is only viable for a few days after it’s manufactured. One pharmaceutical company is racing against the clock to deliver it to patients in time. Novartis manufacturing associate checking punches at compressing machine. Source: Novartis In 2010, a...
by University of East Anglia Credit: Unsplash/CC0 Public Domain Scientists at the University of East Anglia are a step closer to creating a new generation of light-activated cancer treatments. The futuristic-sounding treatment would work by switching on LED lights embedded close to a tumor, which would then activate biotherapeutic drugs. These new treatments would be...
The find could lead to more effective treatments for childhood obesity and cancer. While the research was in fruit fly larvae, being able to speed up or slow down lipid metabolism could have significant implications for human health, says Hua Bai, an associate professor of genetics, development and cell biology at Iowa State University. “We’ve identified what’s...
by CU Anschutz Medical Campus ENI ablates the immune response to combined radiation and immunotherapy. A Schematic of the experimental design for gross tumor irradiation with or without elective nodal irradiation (ENI). Mice were implanted both in the buccal and in the flank on day 0 post-implantation (DPI). Stereotactic body irradiation (SBRT) was given when...
by Josh Barney, University of Virginia Overview of KSTAR algorithm. First, we heuristically prune dense and highly overlapping weighted kinase-substrate prediction graphs from NetworKIN into many sparse, binary graphs. Statistical enrichment is calculated for an experiment that has a defined set of phosphorylation sites for every kinase across all networks using a hypergeometric distribution. We...
by University of Gothenburg Chandrasekhar Kanduri and Meena Kanduri, Institute of Biomedicine, Sahlgrenska Academy at the University of Gothenburg. Credit: Elin Lindström Researchers at the University of Gothenburg have identified a previously unknown mechanism controlling tumor growth in cultured cells and mice. This discovery may potentially enable future development of new drugs against a range...
