A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression. Previous studies have showed blocking the receptor can slow tumor growth and metastasis in certain cases. However, the development of drugs (inhibitors) has...
Tag: <span>Cancer</span>
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Bodywide immune response important for fighting cancer, researchers say
Edgar Engleman and his colleagues have found that a systemwide immune response is needed to effectively attack a tumor. Fighting off cancer requires the concerted efforts of immune molecules throughout the body, rather than just in the tumor itself, according to a new study of laboratory mice by researchers at the Stanford University School of...
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Cancer researchers stumble onto drugs’ fat-blasting powers
The real test will be if the mouse study can be reproduced in humans While the scientific inquiry process is generally linear and highly regimented, every once in awhile, happenstance works its way in. That’s just what happened when researchers at the Mayo Clinic were studying the influence obesity has over cancer treatments and found,...
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Double-barreled drug strategy cancels cancer’s backup plans
Cutting off cancer cells’ fuel sources causes the tumor (blue area above) to “eat” itself (occurring in the green spots), and delivering a second hit to its backup fuel sources has been shown to kill the cells Cancer is a crafty foe. Scientists have long tried to starve out tumors by cutting off their access to...
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Scripps Florida Scientists Uncover New Way to Defeat Therapy-Resistant Prostate Cancer
JUPITER, FL – December 29, 2016 – A new study led by scientists from the Florida campus of The Scripps Research Institute (TSRI) sheds light on a signaling circuit in cells that drives therapy resistance in prostate cancer. The researchers found that targeting the components of this circuit suppresses advanced prostate cancer development. The study,...
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Cancers Evade Immunotherapy By ‘Discarding the Evidence’ of Tumor-Specific Mutations
Discovery could explain widespread acquired resistance among patients treated with immune checkpoint blockade drugs. T-cells attacking a cancer cell. Results of an initial study of tumors from patients with lung cancer or head and neck cancer suggest that the widespread acquired resistance to immunotherapy drugs known as checkpoint inhibitors may be due to the elimination...
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New study explains how low-dose aspirin may prevent cancer
Cancer is a leading cause of morbidity and death worldwide, and its prevalence is predicted to increase in the next few years. Cancer prevention strategies include making healthy lifestyle choices and getting tested if at risk. New research suggests that a small dose of aspirin may help prevent the formation of cancer cells and explains...
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Predicting throat cancer recurrence with a blood test
Researchers found that patients whose oropharyngeal cancer recurred had higher levels of antibodies for two proteins, E6 and E7, which are found in HPV-fueled cancers. The finding suggests a potential blood-based marker that could predict when cancer is likely to return. A new study suggests the possibility of predicting at its earliest stages when a...
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Detecting Cancer cells using Graphene- First of its kind study
What can’t graphene do? You can scratch “detect cancer” off of that list. By interfacing brain cells onto graphene, researchers at the University of Illinois at Chicago have shown they can differentiate a single hyperactive cancerous cell from a normal cell, pointing the way to developing a simple, noninvasive tool for early cancer diagnosis. “This...
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Predicting throat cancer recurrence with a blood test
Study identifies a biomarker that rises just before patients’ cancer comes back — which could provide a window for earlier treatment Summary: Researchers found that patients whose oropharyngeal cancer recurred had higher levels of antibodies for two proteins, E6 and E7, which are found in HPV-fueled cancers. The finding suggests a potential blood-based marker that...