by Sritama Bose, Indian Institute of Science Schematic showing the mechanism by which SIRT6 regulates fatty acid uptake through PPARγ transcription factor in the heart. Credit: Khan et al., 2021/Cell Reports Fatty acids are formed when fat breaks down during digestion. While many of the body’s organs use glucose as their primary energy source, the heart...
by Vanessa McMains, Johns Hopkins University Photomicrograph showing heart tissue taken from the biopsy of a heart attack patient. Johns Hopkins Medicine researchers have shown that after a heart attack, cardiac muscle cells produce lots of CHIP (seen as green in the photo), a protein that clears away the “trash” of misfolded, damaged proteins to improve...
