Unusually small antibodies, targeted to the tumor micro-environment, curb melanoma and colon cancer in mouse models BOSTON CHILDREN’S HOSPITAL In 1989, two undergraduate students at the Free University of Brussels were asked to test frozen blood serum from camels, and stumbled on a previously unknown kind of antibody. It was a miniaturized version of a...
Tag: <span>Causes of Cancer</span>
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Superfast DNA replication causes damage in cancer cells
Inhibitors of PARP proteins are used in cancer treatment. It emerges that PARP inhibitors exert their effect by accelerating DNA replication to a speed at which DNA damage occurs. The two strands of DNA’s double helix unwind to be copied, with a structure called a replication fork forming at the point of separation. The speed...
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Researchers Uncover What Causes Cancer Cells to Spread and How We Can Slow It
IN BRIEF Johns Hopkins University researchers identified a key mechanism behind one of cancer’s deadliest traits. By understanding how metastasis works, their study presents new possibilities for preventing the spread of cancer in the body. UNDERSTANDING CANCER CELLS Treating cancer can be tricky: for one, cancer cells tend to spread quickly, known as metastasis — a...