by The Wistar Institute Wistar’s Dr. Dario Altieri. Credit: The Wistar Institute According to a study by The Wistar Institute, the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks tumor cell movement, reducing primary and metastatic tumor growth. These findings, published today...
Tag: <span>cell metabolism</span>
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Study unveils the intricate way two proteins interact to promote cell movement, metastasis
Posted Today When cells in our bodies need to move—to attack infection or heal a wound, for example—cellular proteins send and receive a cascade of signals that directs the cells to the right place at the right time. It’s a process cancer cells can hijack to spread to new tissues and organs. Now, a team...
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Immune system can be modulated by targeted manipulation of cell metabolism
In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death. Scientists from the Medical University of Vienna and Max F. Perutz Laboratories of MedUni Vienna and the University of Vienna, supervised...