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Team unveils widespread tumor suppression mechanism that stops cancer progression by interfering with cell metabolism
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Team unveils widespread tumor suppression mechanism that stops cancer progression by interfering with cell metabolism

by  The Wistar Institute Wistar’s Dr. Dario Altieri. Credit: The Wistar Institute According to a study by The Wistar Institute, the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks tumor cell movement, reducing primary and metastatic tumor growth. These findings, published today...

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Immune system can be modulated by targeted manipulation of cell metabolism

In its attempt to fight a serious bacterial infection, caused by listeria, for example, the immune system can become so over-activated that the resulting inflammatory response and its consequences can quickly lead to death. Scientists from the Medical University of Vienna and Max F. Perutz Laboratories of MedUni Vienna and the University of Vienna, supervised...