MAY 31, 2024 by University of Texas M. D. Anderson Cancer Center Credit: Unsplash/CC0 Public Domain Researchers from The University of Texas MD Anderson Cancer Center presented positive clinical results from two studies today at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting. The findings highlight strong remission and response rates and offer...
by DGIST (Daegu Gyeongbuk Institute of Science and Technology) Schematic diagram of the MBP technology in NK cells and expected role in the tumor site. (A) Schematic illustration of cytokine engineered MBP NK cells and functional difference between parental NK-92 cells and MBP NK cells. Because of self-stimulation via MBP IL-2, MBP NK cells can...
by Atrium Health Wake Forest Baptist Credit: CC0 Public Domain Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage. Recently identified by the Food and Drug Administration as a public health crisis, osteoarthritis affects more than 520...
by Texas Heart Institute Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial in patients with heart failure to date. The therapy benefited patients by reducing the risk of heart attack and stroke and improving the heart’s ejection fraction, especially in patients who have high levels of inflammation....
by National University of Ireland, Galway Credit: Pixabay/CC0 Public Domain University of Galway, in collaboration with the NEPHSTROM Consortium, has announced promising results from a new cell therapy trial for people living with diabetes. The NEPHSTROM clinical trial is taking the first steps to investigate the value of a novel cell therapy for adults who...
by European Society for Medical Oncology Lead author Professor John Haanen. Credit: European Society for Medical Oncology A novel treatment strategy with personalized cell therapy significantly improves progression-free survival compared to standard immunotherapy in patients with advanced melanoma, according to ground-breaking results reported at the ESMO Congress 2022 from the phase 3 M14TIL trial. “This study...
by Washington University School of Medicine A new study from Washington University School of Medicine in St. Louis suggests a simple blood test—administered before CAR-T cell treatment is initiated—may identify which patients are predisposed to developing neurotoxic side effects after CAR-T cell therapy. Severe side effects can include seizures, brain swelling and strokes. Evidence of a...
by Nancy Fliesler, Children’s Hospital Boston Graphical abstract. Credit: Cell Reports (2022). DOI: 10.1016/j.celrep.2022.110662 Many serious pulmonary diseases, including genetic lung diseases, lack an effective treatment other than the most extreme: lung transplant. A team at Boston Children’s Hospital envisions a much better option: cell therapy, using lung stem cells created from patients’ own cells to repair...
by Julia Evangelou Strait, Washington University School of Medicine A study by researchers at Washington University School of Medicine in St. Louis shows that treatment with an immunity boosting protein called interleukin 7 (IL-7) after an infusion of genetically modified T cells causes the cancer-fighting CAR-T cells to grow in number and become more effective at...
by Northwestern University Mice treated with novel approach to cell therapy saw dramatic shrinkage in tumors compared to those treated with traditional cell therapy approaches. Credit: Please credit Shana Kelley Lab / Northwestern University Northwestern University scientists have developed a new tool to harness immune cells from tumors to fight cancer rapidly and effectively. Their...
