by Cedars-Sinai Medical Center Credit: CC0 Public Domain The Cedars-Sinai investigators discovered several key components in the control of telomerase reverse transcriptase, or TERT, expression, one of the necessary component proteins of telomerase. High levels of TERT are found in several cancer types, the result of mutations in DNA that control the levels of TERT in...
Tag: <span>Cellular pathway</span>
Researchers link cellular transport pathway to aggressive brain cancer
ROCKEFELLER UNIVERSITY PRESS IMAGE: COMPARED WITH CONTROL MICE (TOP TWO ROWS), BRAIN TUMORS (GREEN) GROW FASTER IN THE ABSENCE OF RAB35 (BOTTOM TWO ROWS). CREDIT: ©2021 KULASEKARAN ET AL. ORIGINALLY PUBLISHED IN JOURNAL OF CELL BIOLOGY. Researchers at McGill University have identified a new cellular pathway that limits the growth and spread of brain tumors by controlling...
Cellular pathway of genetic heart disease similar to neurodegenerative disease
MAYO CLINIC ROCHESTER, Minn. — Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease ? and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy. Dilated cardiomyopathy...