Tag: <span>Chaperones</span>

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Unraveling one of prion disease’s deadly secrets
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Unraveling one of prion disease’s deadly secrets

AMHERST, Mass. – A molecular biologist at the University of Massachusetts Amherst who has for decades studied the nightmarish group of fatal diseases caused by prions – chronic wasting disease in deer, mad cow in cattle and its human analog – credits a middle-of-the-night dream for a crucial insight, a breakthrough she hopes could lead...

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Quality control in immune communication: Chaperones detect immature signaling molecules

by Technical University Munich The cells of our immune system constantly communicate with one another by exchanging complex protein molecules. A team led by researchers from the Technical University of Munich (TUM) has now revealed how dedicated cellular control proteins, referred to as chaperones, detect immature immune signaling proteins and prevent them from leaving the cell. The body’s defenses systems have to react quickly whenever pathogens...