by Impact Journals LLC Resveratrol increases in vitro rhythmic gene mRNA expression of core clock components in human adipose-derived progenitor cells (APCs) from older participants. Credit: Aging (2024). DOI: 10.18632/aging.205292A new research paper was published on the cover of Aging titled, “Effects of resveratrol on in vitro circadian clock gene expression in young and older...
Tag: <span>circadian clock</span>
A night and day difference: Circadian clock may protect aging eyes
by Purdue University Fruit flies give insight into age-related changes in human vision. A team of researchers discovered the circadian clock plays a significant role in protecting eyes from retinal degeneration. The team studied fruit flies, which serve as a good model for the human retina. Vikki Weake, associate professor of biochemistry in Purdue’s College...
The circadian clock in heart failure
by Baylor College of Medicine Credit: Unsplash/CC0 Public Domain Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition. A research team at Baylor College of Medicine and collaborating institutions investigated the function of the protein Rev-erbα/β, a key...
Known regulatory gene appears to be a master gear in the circadian clock
by UT Southwestern Medical Center Microscopic image of the mouse suprachiasmatic nucleus, the brain region responsible for controlling circadian rhythms. Credit: UT Southwestern Medical Center A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain’s circadian...
A world first in circadian clock manipulation
INSTITUTE OF TRANSFORMATIVE BIO-MOLECULES (ITBM), NAGOYA UNIVERSITY IMAGE: TRANS AND CIS ISOMERS OF AZOBENZENE DETERMINE THE CHANGE IN THE CIRCADIAN PERIOD THROUGH THEIR INTERACTION WITH THE CRY1 CLOCK GENE CREDIT: ISSEY TAKAHASHI The Nagoya University Institute of Transformative Bio-Molecules (WPI-ITbM) research team of Designated Associate Professor Tsuyoshi Hirota, Postdoctoral Fellow Simon Miller, Professor Kenichiro Itami and graduate...