Business Announcement INSILICO MEDICINEAMYOTROPHIC LATERAL SCLEROSIS (ALS) IS A FATAL TYPE OF MOTOR NEURON DISEASE CHARACTERIZED BY PROGRESSIVE DEGENERATION OF NERVE CELLS IN THE SPINAL CORD AND BRAIN. CREDIT: INSILICO MEDICINE Two years after the collaboration was announced between Insilico and 4B Technologies, the AI-discovered ALS drug, FB1006, completed patient enrollment for the IIT study.From...
Tag: <span>Clinical trial</span>
New treatment for a rare and aggressive cancer improves survival rates in breakthrough clinical trial
by Queen Mary, University of London Credit: Pixabay/CC0 Public DomainAn innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but rapidly fatal type of cancer with few effective treatment options, according to results from a clinical trial led by Queen Mary University of London. The findings have been published in JAMA Oncology....
Clinical trial shows rheumatoid arthritis drug could prevent disease
by King’s College London Credit: Unsplash/CC0 Public DomainA drug used to treat rheumatoid arthritis could also prevent the disease in individuals deemed to be at risk. Results from a Phase 2b clinical trial, published today in The Lancet by researchers led by King’s College London, provide hope for arthritis sufferers after it was shown that the...
In a clinical trial, blood thinners added to clot-busting medication did not improve stroke outcomes
by American Heart Association Credit: CC0 Public DomainGiving blood thinners in addition to clot-busting medications to people with ischemic strokes (clot-caused strokes) did not improve their outcomes 90 days later, according to preliminary late-breaking science presented today at the American Stroke Association’s International Stroke Conference 2024. These results are from the MOST (Multi-Arm Optimization of Stroke...
mRNA skin cancer therapy halves risk of death in clinical trial
By Michael Irving mRNA technology has proven promising against skin cancer in a new phase 2b clinical trial Depositphotos Moderna has announced the results of a Phase 2b trial investigating its mRNA treatment for skin cancer, and it continues a streak of promising news. When paired with an immunotherapy, the treatment significantly reduced the risks of...
World-first: Daily tablet slows diabetes progression in clinical trial
By Paul McClure A clinical trial has shown that a rheumatoid arthritis drug can preserve the pancreas’ ability to produce insulin in newly diagnosed type 1 diabetics Depositphotos A world-first clinical trial has found that baricitinib, a drug commonly prescribed for rheumatoid arthritis, preserved the pancreatic cells’ ability to produce their own insulin and slowed the...
Clinical trial highlights possible treatment for anemia in myelodysplastic neoplasms
by Anne Grimm, Leipzig University Credit: Pixabay/CC0 Public Domain In patients affected by myelodysplastic neoplasms, the body does not produce enough functional blood cells. Patients suffer from anemia—a lack of red blood cells and hemoglobin—which can progress to acute leukemia. Imetelstat, a new agent beyond the current standard of care, may help to avoid blood transfusions,...
Clinical trial results suggest potential new treatment for primary biliary cholangitis
by Liam Connolly, UC Davis Credit: Unsplash/CC0 Public DomainAn international clinical trial involving UC Davis Health suggests the investigational drug Elafibranor is a potential novel treatment for patients with the rare, autoimmune disease primary biliary cholangitis. Results from the clinical trial showed significant improvements in biomarkers of disease progression. Patients also reported positive outcomes. The...
DRUG DISCOVERY PAVES WAY FOR PANCREATIC CANCER CLINICAL TRIAL
NOVEMBER 17TH, 2023POSTED BY LESLIE ORR-ROCHESTER In mice and in tissue studies, when researchers suppressed Netrin-1 with the anti-cancer drug (NP137), cancer was less likely to spread and cancer cell death occurred. (Credit: Getty Images) Laboratory findings have set the stage for a clinical trial investigating a drug for pancreatic cancer that has spread to the liver....
First human clinical trial for pill-sized device that monitors breathing from the gut
by Cell Press VMPill shown in a clear gel capsule for ease of visualization of internal components. Credit: Ben Pless Scientists have developed an ingestible device that can safely monitor vital signs like breathing and heart rate from inside humans. The tool, described November 17 in the journal Device, has the potential to provide accessible and...