by Dennis Thompson An experimental drug appears to outperform the trendy medications Wegovy and Ozempic for both weight loss and diabetes control, a pair of early clinical trials shows. Retatrutide helped people with obesity drop about one-quarter of their starting weight, on average, during 48 weeks taking the drug, according to phase 2 trial results published online...
David Warmflash, MD February 03, 2023 When I was a child, I watched syndicated episodes of the original Star Trek. I was dazzled by the space travel, sure, but also the medical technology. A handheld “tricorder” detected diseases, while an intramuscular injector (“hypospray”) could treat them. Sickbay “biobeds” came with real-time health monitors that looked futuristic at...
Max Kozlov Surgeons at New York University transplanted pig kidneys into legally dead people on ventilators for the first time late last year.Credit: Joe Carrotta for NYU Langone Health In the months since physicians showed that it is possible to transplant pig organs into humans, researchers have been calling for US regulators to allow clinical...
GEORGE INSTITUTE FOR GLOBAL HEALTH Findings from preliminary tests of a new dialysis system have confirmed its ability to make sterile, medical grade water to provide an affordable, accessible home-based treatment option for patients with kidney failure. This means that the Ellen Medical Devices Point-of-Care dialysis system can create peritoneal dialysis fluid (a mix of...
By Laura Lovett January 26, 202211:56 am Photo courtesy of Royal Philips Med tech giant Royal Philips is rolling out a new at-home ECG system for decentralized clinical trial use. The company is pitching this new technology as a way for clinical trial participants to record ECG data without traveling to a clinical site or...
by ZACHARY BRENNAN CMS on Tuesday said it will only pay for Biogen’s Aduhelm and other FDA-approved anti-amyloid monoclonal antibodies for Alzheimer’s disease under CMS-approved randomized controlled trials. In a draft national coverage decision, which insurers nationwide are likely to follow, CMS said it’ll be looking for randomized controlled trials that “demonstrate a clinically meaningful benefit in cognition...
by Emily Leclerc, University of Wisconsin-Madison A hallmark of Alexander disease is the buildup of abnormal proteins called Rosenthal fibers, pictured here (red) in brain tissue from a study of a rat model of the disease. The study identified a potential treatment and helped provide early data for a human clinical trial now underway. Credit: Tracy...
July 16, 2021, 9.04am EDT Judy MartinProfessor of Pediatrics, University of Pittsburgh The freedom of going mask-free is still a ways off for kids under age 12. Juan Monino/E+ via Getty Images Now that two-thirds of all adults in the United States have received at least one dose of a SARS-CoV-2 vaccine as of mid-July 2021,...
by Tohoku University Neurodegenerative diseases such as Alzheimer’s disease and dementia with Lewy body (DLB) are caused by the accumulation of aggregated amyloid-beta and α-synuclein, respectively. The aggregated proteins impaired the proteasome activity, thereby exacerbating neuronal death. On the other hand, we developed a novel T-type calcium channel enhancer SAK3 in 2017. Since the T-type calcium...
By Sally Robertson, B.Sc. Apr 28 2021 Researchers in the UK and United States have demonstrated the efficacy of one dose of either the Pfizer-BioNTech or Oxford-AstraZeneca vaccine against infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a real-world community setting in the UK. The novel SARS-CoV-2 virus is the agent responsible for the coronavirus...
