JUNE 5, 2024 by Noah Brown, Massachusetts General Hospital Resting-state functional connectivity after THC intoxication. Credit: Neuropsychopharmacology (2024). DOI: 10.1038/s41386-024-01876-5A new study led by investigators from Massachusetts General Hospital reveals that the main psychoactive component in cannabis or marijuana disrupts the normal connections and activity of the brain’s prefrontal cortex, a region that is crucial...
REGENSTRIEF INSTITUTE INDIANAPOLIS – Mild cognitive impairment, which occurs in about one in six individuals in the U.S., age 65 and older, remains substantially underdiagnosed, especially in disadvantaged populations. Convened by the non-profit UsAgainstAlzheimer’s, The Brief Cognitive Assessment Work Group, is composed of 15 clinicians, researchers and health systems administrators from across the U.S. The group advocates for...
Megan Brooks May 01, 2023 Screening for cognitive impairment should be part of multidisciplinary care for stroke survivors, the American Heart Association (AHA) says in a new scientific statement. “Cognitive impairment after stroke is very common, is associated with other post-stroke outcomes, and often has significant impact on the quality of life,” Nada El Husseini, MD, MHSc, chair of...
by Salk Institute Electron microscopic image of neurons in the brain showing the presynaptic boutons (yellow), mitochondria (purple), and synapses (blue). Credit: Salk Institute Brains are like puzzles, requiring many nested and co-dependent pieces to function well. The brain is divided into areas, each containing many millions of neurons connected across thousands of synapses. These synapses,...
by Matt Crouch, Auburn University An Auburn University study tested the effects the consumption of extra virgin olive oil or refined olive oil had on participants experiencing mild cognitive impairment. Credit: Auburn University at Montgomery Extra virgin olive oil may have positive effects on individuals with mild cognitive impairment, according to a recently completed study...
Sue Hughes February 13, 2023 A combination of two drugs has shown promising results, including a reduction in cognitive impairment in patients who have had a lacunar stroke, and is seen as a new therapeutic approach for patients with cerebral small vessel disease. The drugs — isosorbide mononitrate and cilostazol — stabilize endothelial function, which is a new therapeutic target for patients...
by University of Tsukuba Credit: Ljupco Smokovski/Shutterstock Physical balance may not seem like it would be associated with cognitive function. But now, researchers from Japan have developed a new way to predict cognitive problems according to physical balance. In a study recently published in BMC Geriatrics, researchers from the University of Tsukuba have revealed a new measure...
Reviewed by Emily Henderson, B.Sc. Dec 19 2022 A recent study by a team comprising researchers from the National University of Singapore (NUS) and the National University Health System (NUHS) revealed that low levels of ergothioneine (ET) in blood plasma may predict an increased risk of cognitive impairment and dementia, suggesting possible therapeutic or early...
by Institute for Basic Science The inflammatory response of RA causes autophagy in FLSs to produce putrescine, which intensifies inflammation of GABA and H2O2 through the MAO-B in the joint. In chronic inflammation, increased IL-1β passes through a loose blood-brain barrier and enters the brain. Increased IL-1β in the hippocampus causes cognitive impairment by activating astrocytes...
by University of Toronto Credit: Pixabay/CC0 Public Domain A new nationally representative study published online in the Journal of Alzheimer’s Disease Reports found hearing impairment and vision impairment to be independently associated with cognitive impairment. After considering sex, age and other socio-demographic characteristics, older adults with hearing impairment had more than double the odds of cognitive impairment, while those with vision...
