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A common metabolite may help treat autoimmune diseases
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A common metabolite may help treat autoimmune diseases

by Hokkaido University In mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to untreated mice . Credit: Kuniyuki Aso, et al. Nature Communications, February 27, 2023 Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which...