By CHILDREN’S HOSPITAL OF PHILADELPHIA AUGUST 13, 2023 Researchers have discovered that the SARS-CoV-2 virus can negatively impact mitochondrial genes, causing dysfunction in multiple organs beyond the lungs. This finding, suggesting that COVID-19 should be viewed as a systemic disorder, highlights potential new therapeutic targets, including the microRNA 2392. Mitochondrial function in the lungs showed recovery, but this...
Tag: <span>COVID-19</span>
Patients hospitalized with COVID-19 found to face nearly twice the rates of death after discharge as patients with flu
by Beth Israel Deaconess Medical Center Risk of all cause death and readmission after live discharge from covid-19 and Influenza related hospital admission. Credit: BMJ (2023). DOI: 10.1136/bmj-2023-076222 As of June 2023, more than 1.1 million Americans have died of COVID-19. Adults older than 65 —who make up just 16 percent of the population—account for more than 75...
COVID-19 hospitalizations in the US are on the rise again, but not like before
by Carla K. Johnson A sign announcing a face mask requirement is displayed at a hospital in Buffalo Grove, Ill., Friday, Jan. 13, 2023. COVID-19 hospital admissions are inching upward in the United States since early July 2023. It’s a small-scale echo of the three previous summers. Credit: AP Photo/Nam Y. Huh Here we go...
COVID-19: All You Need to Know About EG.5.1 — The UK-Hitting Omicron Sub-Variant Already Present in India
By TWC India Edit Team 3 hours ago TWC India Representational image(TOI/BCCL) Like a vengeful little factory, the COVID-causing Omicron variant has been pushing out new sub-variants since it first emerged in 2022. And its latest product, the EG.5.1 or ‘Eris’, has already been detected in at least 45 countries, including India. Reports of a new...
Scientists begin to untangle how COVID-19 affects brain cells
by The Francis Crick Institute Astrocytes, endothelial cells, pericytes and microglia expression of ‘entry factors’ (ACE2, TMPRSS2, NRP1 and CD147) which are receptors in the cells that the COVID-19 virus uses to enter, as shown by the colors in the image. Credit: Alize Proust, Journal of Neuroinflammation Researchers at the Francis Crick Institute have shown in lab-based...
Scientists develop breath test that rapidly detects COVID-19 virus
by Jim Dryden July 31, 2023 CHAKRABARTY LAB Benjamin Sumlin, PhD, a senior scientist at Washington University in St. Louis, blows into a device designed by researchers at the university. The device — a breath test that uses a biosensor — could become a tool for use in doctors’ offices to quickly diagnose people infected...
Moderna is safest, most effective mRNA vaccine against COVID-19 for older adults, study shows
by Brown University Credit: CC0 Public Domain While mRNA vaccines against COVID-19 have been found to be safe and effective for the general population, in-depth evidence about safety and effectiveness for older adults and individuals with chronic health conditions is more limited. To address that gap, a team led by Brown University researchers conducted the largest...
Commonly used gout drug found effective against COVID-19
by David Mitchell, University of Georgia Time to viral load clearance. Shown is a Kaplan–Meier plot with 95% Hall–Wellner bands of time to clearance of SARS-CoV-2 RNA by treatment. Quartiles are derived from Kaplan–Meier product limit estimates. P-value is based on the Log-Rank test for comparing between treatment groups. Credit: Viruses (2023). DOI: 10.3390/v15071508 An anti-inflammatory drug commonly...
COVID-19 can cause inflammation that results in bone loss, higher fracture risk
by Nadine A Yehya, University of California 3D renderings of L5 lumbar spine segments showing SARS-CoV-2 induced systemic bone loss in both male and female mice. Credit: University of California A UC Davis Health study that looked at acute bone loss in mice who had COVID-19 showed that SARS‐CoV‐2 infection can cause significant changes in...
Long COVID not caused by COVID-19 immune inflammatory response, new research finds
by University of Bristol Ongoing symptoms at three months and associations with immune profiles. (A, B) The percentage of patients with mild (N=17), moderate (N=32), and severe (N=14) coronavirus disease-19 (COVID-19) who reported the indicated symptom (A) or number of symptoms (B) at three months are indicated with white, grey, and black bars, respectively. Statistics were calculated...