by University of South Florida Three configurations of active sites where inhibitor GC-376 binds with the COVID-19 virus’s main protease (drug target Mpro), as depicted by 3D computer modeling. Credit: Image generated by Yu Chen, University of South Florida Health, using X-ray crystallography As the death toll from the COVID-19 pandemic mounts, scientists worldwide continue...
The combination of immunotherapy (Tecentriq) and chemotherapy (Abraxane) was given accelerated approval for triple-negative breast cancer that is locally advanced or has metastasized, cannot be surgically removed, and is programmed death-ligand 1-postive, CNNreported. A study published last October in the New England Journal of Medicine revealed a median progression-free survival of 7.4 months among patients...
Acetaminophen kicks off widespread glutathionylation, researchers find AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound that covalently binds to proteins...
