by Queen Mary, University of London Credit: CC0 Public Domain A genetic predisposition to having lower insulin production and less healthy fat distribution are major causes of early-onset type 2 diabetes in British Asian people. According to new research from Queen Mary University of London, these genetic factors also lead to quicker development of health complications,...
Tag: <span>Diabetes</span>
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Genetic High Cholesterol Condition Poses Diabetes Risk
A new review found that a genetic condition that puts people at a risk for high cholesterol is not protective against type 2 diabetes (T2D), despite previous studies suggesting the opposite. Data from the European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration (EAS FHSC) registry indicate that most individuals with heterozygous familial hypercholesterolemia are at a...
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GLP-1 receptor agonist and SGLT2 inhibitor prescribing in people with type 1 diabetes
About The Study: Prescribing for both glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter 2 (SGLT2) inhibitors in a type 1 diabetes (T1D) population identified in a database increased between 2010 and 2023. Differences in characteristics of the overall T1D population and those newly prescribed the medications are often associated with elevated cardiorenal risk profiles, suggesting...
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Non-invasive ECG device for diabetics live-monitors your blood sugar
An ECG signal is used to predict blood sugar levels Singular Wings View 2 Images A new continuous glucose monitor (CGM) that is not only non-invasive but that predicts blood sugar levels from ECG data promises to shake up diabetes management. The device is being showcased at the 2024 Taiwan Innotech Expo. Continuous glucose monitors...
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Study finds tuberculosis changes liver metabolism and could promote diabetes
Scientists from the University of Leicester have discovered that tuberculosis disrupts glucose metabolism in the body University of Leicester Professor Andrea Cooper from the University of Leicester Credit: University of Leicester Scientists from the University of Leicester have discovered that tuberculosis disrupts glucose metabolism in the body. The findings, which have now been published in PLoS...
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‘Smart’ insulin prevents diabetic highs — and deadly lows
Crystals of insulin. A new kind of insulin can modify its activity in response to glucose levels in the blood.Credit: Antonio Romero/Science Photo Library Scientists have designed a new form of insulin that can automatically switch itself on and off depending on glucose levels in the blood. In animals, this ‘smart’ insulin1 reduced high blood-sugar concentrations...
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The silent threat of sarcopenia among elderly type 2 diabetes patients
Credit: CC0 Public Domain As global populations age, the prevalence of type 2 diabetes and its associated complications, such as sarcopenia, continues to rise. Sarcopenia, which involves the progressive decline of muscle mass and strength, is common among older adults and is linked to various negative health outcomes, including increased risk of falls, frailty, and...
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Researchers identify signaling mechanism that damages cells in diabetic kidney disease
Researchers identify signaling mechanism that damages cells in diabetic kidney diseaseUpregulation of FXII correlates with impaired kidney function in human DKD. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-52214-8Diabetic kidney disease, a complication of diabetes, is considered the leading cause of chronic kidney disease and kidney failure worldwide. It is associated with changes in the structure and...
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How diabetes risk genes make cells less resilient to stress
A graphical representation of pancreatic islet cells attached to strings bobbing up and down like a marionette. Credit: Gloria Fuentes The cells in your pancreas, like people, can only handle so much stress before they start to break down. Certain stressors, such as inflammation and high blood sugar, contribute to the development of type 2...
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Trial finds metabolic risk contributes to diabetes onset in people with HIV
For people with HIV (PWH) with low-to-moderate atherosclerotic cardiovascular disease (ASCVD) risk, metabolic risk factors contribute to new-onset diabetes mellitus (DM) among those treated with pitavastatin or placebo, according to a study published online Oct. 8 in the Annals of Internal Medicine. Kathleen V. Fitch, from Massachusetts General Hospital and Harvard Medical School in Boston, and colleagues examined...