Pamela Goodwin has received hundreds of emails from patients asking if they should take a cheap, readily available drug, metformin, to treat their cancer. It’s a fair question: Metformin, commonly used to treat diabetes, has been investigated for treating a range of cancer types in thousands of studies on laboratory cells, animals, and people. But Goodwin, an epidemiologist...
Tag: <span>Diabetes drug</span>
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The brain aged more slowly in monkeys given a cheap diabetes drug
12 September 2024 By Max Kozlov Cellular measures of ageing changed more slowly in the liver, brain and other tissues of monkeys taking the drug metformin.Credit: Vachira Vachira/NurPhoto/Getty A low-cost diabetes drug slows ageing in male monkeys and is particularly effective at delaying the effects of ageing on the brain, finds a small study that...
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Diabetes drug helps the immune system recognize reservoirs of HIV, study discovers
September 10, 2024 by Bruno Geoffroy, University of Montreal Hospital Research Centre Graphical abstract. Credit: iScience (2024). DOI: 10.1016/j.isci.2024.110670Metformin, a drug used to treat type 2 diabetes, could help deplete the viral reservoir and eliminate it entirely in people living with HIV who receive antiretroviral therapy, Canadian researchers say in a new study. In 2021,...
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Research shows diabetes drug could reduce dementia risk—here’s how the two diseases may be linked
September 4, 2024 by Steve Macfarlane, The Conversation Credit: Unsplash/CC0 Public DomainA Korean study published recently suggests that people with type 2 diabetes who are prescribed a particular class of drug might be at a significantly lower risk of dementia. The researchers compared the health outcomes of more than 110,000 people aged 40–69 with type...
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Data provide new perspective for understanding the antidepressant-like effects of a diabetes drug
by Wiley Credit: Pixabay/CC0 Public DomainResearch in animals has shown that the diabetes drug dulaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist may reduce symptoms of depression. A new study published in Brain and Behavior reveals the mechanisms that are likely involved. By conducting a range of tests in mice treated with and without dulaglutide,...
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Popular diabetes drug may also reduce the risk of severe liver disease
by Karolinska Institutet Credit: Pixabay/CC0 Public DomainOzempic and other GLP1 agonists are associated with a reduced risk of developing cirrhosis and liver cancer in people with type 2 diabetes and chronic liver disease, according to a nationwide study from Karolinska Institutet in Sweden published in the journal Gut. GLP1 agonists like Ozempic reduce blood sugar levels...
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Diabetes drug may significantly lower women’s risk of substantial weight gain after giving up smoking
by British Medical Journal Credit: Pixabay/CC0 Public Domain The diabetes drug dulaglutide (Trulicity) may significantly lower a woman’s risk of substantial weight gain after she has given up smoking, finds a secondary analysis of clinical trial data, published in the open access journal BMJ Nutrition Prevention & Health. Women seem to be five times as likely...
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New Case Western Reserve University study finds diabetes drug may reduce risk for colorectal cancer
Peer-Reviewed Publication CASE WESTERN RESERVE UNIVERSITY NATHAN BERGER CREDIT: CASE WESTERN RESERVE UNIVERSITY CLEVELAND—A groundbreaking study by researchers at Case Western Reserve University suggests a class of medications used to treat type 2 diabetes may also reduce the risk of colorectal cancer (CRC). The findings, published today (Dec. 7) in the journal JAMA Oncology, support...
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Synergistic effect of a traditional Chinese medicinal compound on existing diabetes drug found
by Justin Jackson, Medical Xpress Discovery and inhibition of a gut microbial–host isozyme to regulate host metabolism. Differences in the gut microbiota may explain why some individuals respond to antidiabetic DPP4 inhibitors but others do not. An activity-based enzyme activity screening system identified gut microbial DPP4 isozymes that can decrease active GLP-1 but cannot be...
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Diabetes Drug Tied to Lower Dementia Risk
Megan Brooks February 16, 2023 Treatment with the thiazolidinedione pioglitazone may offer the greatest protection against dementia for older adults with newly diagnosed type 2 diabetes mellitus (T2DM) who have a history of stroke or ischemic heart disease, new research suggests. Overall, in a large cohort study from Korea, patients who took pioglitazone were 16% less likely to develop dementia over an average of...