TAMPA, Fla. – September 5, 2018 – Mellitus Health, Inc., the developer of Insulin Insights™, the first FDA-cleared and CE-registered clinician decision-support tool for titrating all types of insulin, all eight standard dosing regimens and 125 combinations of insulin, and Smart Meter LLC, an innovative diabetes management technology and solutions company, announced today a strategic...
Tag: <span>Diabetes</span>
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Miniaturized HTS assay identifies selective modulators of GPR119 to treat type 2 diabetes
A novel high throughput screening (HTS) assay compatible with an ion channel biosensor component was used successfully to identify selective and active small molecule modulators of G protein-coupled receptor 119 (GPR119), a promising target for the treatment of type 2 diabetes and related metabolic disorders. The development of this cell-based HTS assay and its miniaturization...
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Natural ways to improve insulin sensitivity
Insulin sensitivity refers to how sensitive the body’s cells are in response to insulin. Doctors generally consider a high insulin sensitivity to be healthy. Some lifestyle and dietary changes may help improve this sensitivity. Insulin is a hormone that helps control the amount of sugar, or glucose, in the blood. The body’s cells respond to...
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Reprogramming skin cells to repair themselves
Skin grafts are risky in an increasing number of patients, partly due to rising rates of diabetes This method by the Salk Institute could avoid dangerous outcomes UC San Diego biology professor Juan Carlos Izpisua Belmonte explains his work People with severe burns, bedsores or chronic diseases such as diabetes are at risk for developing...
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Comprehensive analysis of body composition and insulin traits associated with intra-pancreatic fat deposition in health and new-onset prediabetes/diabetes after acute pancreatitis
Abstract Current knowledge on biomarkers of intra-pancreatic fat deposition (IFD) is limited. We aimed to analyze comprehensively body composition and insulin traits as biomarkers of IFD in healthy normoglycaemic individuals as well as individuals with new-onset prediabetes and diabetes after acute pancreatitis (NODAP). A total of 29 healthy and 34 NODAP individuals took part in...
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Exercise could delay progression of type 1 diabetes when first diagnosed
The findings of a study led by the University of Birmingham suggests that exercise during the first few months of diagnosis of type 1 diabetes could delay the progression of the condition. Credit: CC0 Public Domain Study participants who continued an active exercise regime after type 1 diagnosis extended their partial remission, also known as the ‘honeymoon’...
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Dectin-1-mediated pain is critical for the resolution of fungal inflammation
Osaka University study shows that the Dectin-1 to TRP channel pathway is a novel signaling mechanism in the onset of pain, and that inhibition of the VNUT ATP transporter blocks candidiasis-mediated pain Osaka, Japan – Candida albicans infection (candidiasis) can cause skin, genital, or oral pain. Many studies have attempted to understand the source of pain in...
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Aspirin disappoints for avoiding first heart attack, stroke
Taking a low-dose aspirin every day has long been known to cut the chances of another heart attack, stroke or other heart problem in people who already have had one, but the risks don’t outweigh the benefits for most other folks, major new research finds. This Thursday, Aug. 23, 2018 photo shows an arrangement of...
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New medications for diabetes management have additional heart benefits, study finds
TORONTO, August 27, 2018 – A drug used to manage diabetes may reduce heart disease and death in people with diabetes regardless of their cholesterol levels and whether they are on a statin therapy, suggests a new analysis of the LEADER trial. IMAGE: A DRUG USED TO MANAGE DIABETES MAY REDUCE HEART DISEASE AND DEATH IN...
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Failing immune system ‘brakes’ help explain type 1 diabetes in mice
Immune reactions are usually a good thing–the body’s way of eliminating harmful bacteria and other pathogens. But people also rely on molecular “brakes,” or checkpoints, to keep immune systems from attacking their own cells and organs and causing so-called autoimmune disease. Now, working with mice, Johns Hopkins researchers have discovered that in the rodent form...