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New tool more accurately uses genomic data to predict disease risk across diverse populations
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New tool more accurately uses genomic data to predict disease risk across diverse populations

by Massachusetts General Hospital Credit: CC0 Public Domain Polygenic risk scores (PRS) are promising tools for predicting disease risk, but current versions have built-in bias that can affect their accuracy in some populations and result in health disparities. However, a team of researchers from Massachusetts General Hospital (MGH), the Broad Institute of MIT and Harvard,...

DNA sites linked with physical differences between sexes now also linked to disease risk
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DNA sites linked with physical differences between sexes now also linked to disease risk

by Public Library of Science Lantern slide of drawings of the male and female body, with grid lines. Made by Alex Gunn & Sons, Melbourne, Victoria, circa 1940s. Credit: Museums Victoria (Public Domain, creativecommons.org/publicdomain/mark/1.0/) Some physical traits that differ between sexes are known to be linked to certain single nucleotide polymorphisms (SNPs) in chromosomes other than...