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New tool improves the search for genes that cause diseases
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New tool improves the search for genes that cause diseases

by University of Chicago DNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHA new statistical tool developed by researchers at the University of Chicago improves the ability to find genetic variants that cause disease. The tool, described in a new paper published January 26, 2024, in Nature Genetics, combines data...

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Why are animal-to-human diseases on the rise?

Graphic showing which animals host the most zoonotic viruses that have also been found in humans. From COVID-19 to monkey pox, Mers, Ebola, avian flu, Zika and HIV, diseases transmitted from animals to humans have multiplied in recent years, raising fears of new pandemics. What’s a zoonosis? A zoonosis (plural zoonoses) is a disease or infection transmitted...

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Screening of osteoporosis lags other diseases

HEBREW SENIORLIFE HINDA AND ARTHUR MARCUS INSTITUTE FOR AGING RESEARCH A new perspective article published in the Lancet Diabetes & Endocrinology has highlightedthat screening and treatment of osteoporosis lags behind other diseases, resulting in significant morbidity, mortality, and economic costs.  Over the past 30 years, there has been tremendous progress in the ability to diagnose osteoporosis, a...

Mapping the hidden connections between diseases
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Mapping the hidden connections between diseases

by Mark Greaves, University College London Credit: University College London A new study led by UCL researchers has identified patterns in how common health conditions occur together in the same individuals, using data from 4 million patients in England. With advancing age, millions of people live with multiple conditions—sometimes referred to as multimorbidity—and the proportion...

Study sheds new light on the link between oral bacteria and diseases
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Study sheds new light on the link between oral bacteria and diseases

by Karolinska Institutet Credit: CC0 Public Domain Researchers at Karolinska Institutet in Sweden have identified the bacteria most commonly found in severe oral infections. Few such studies have been done before, and the team now hopes that the study can provide deeper insight into the association between oral bacteria and other diseases. The study is...

New machine-learning technique for classifying key immune cells has implications for a suite of diseases
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New machine-learning technique for classifying key immune cells has implications for a suite of diseases

by Trinity College Dublin Overview of experimental work. Image created using biorender.com. Credit: eLife (2022). DOI: 10.7554/eLife.77373 Researchers from Trinity College Dublin have developed a new, machine learning-based technique to accurately classify the state of macrophages, which are key immune cells. Classifying macrophages is important because they can modify their behavior and act as pro- or anti-inflammatory agents...

Climate change is making hundreds of diseases much worse
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Climate change is making hundreds of diseases much worse

McKenzie Prillaman Floods, such as this one in Bangladesh, can increase the risk and severity of infectious diseases.Credit: Mamun Hossain/AFP/Getty  Climate change has exacerbated more than 200 infectious diseases and dozens of non-transmissible conditions, such as poisonous-snake bites, according to an analysis1. Climate hazards bring people and disease-causing organisms closer together, leading to a rise...

Cancer research repurposed to expose age-related blood diseases
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Cancer research repurposed to expose age-related blood diseases

by  Institute for Research in Biomedicine (IRB Barcelona) Tools and datasets used to identify cancer driver genes could also advance research in clonal hematopoiesis. Credit: IRB Barcelona Clonal hematopoiesis is a biological process in which a blood stem cell (the population that gives rise to a variety of blood cell types) acquires an advantageous mutation and...

Rapid test delineates diseases with similar symptoms
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Rapid test delineates diseases with similar symptoms

by National Institutes of Health Duplex lateral flow assay for typhoid and malaria. Several drops of human serum are placed in the cartridge at the bottom. As the sample flows across the test strip in the cartridge, the red balls (nanoparticles) detect typhoid creating a red line and the blue nanoparticles detect malaria creating a...

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TRAINING’ YOUR FAT MAY WARD OFF DISEASES AS YOU AGE

How well does your fat function? It isn’t a question that one gets asked very often. Nonetheless, research in recent years suggests that the function of our fat tissue, or adipose tissue, is central to why our bodies decay with age, and strongly linked to human diseases like diabetes 2, cancer, and obesity often develop...