Zinc excess in the body correlates with oxidative stress UNIVERSITY OF CALIFORNIA – RIVERSIDE RIVERSIDE, Calif. — Researchers at the University of California, Riverside, have completed a cross-sectional human studythat compares biomarkers and metal concentrations in the urine of e-cigarette users, nonsmokers, and cigarette smokers. They found that the biomarkers, which reflect exposure, effect, and...
Tag: <span>DNA Damage</span>
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Mutant proteins linked to DNA damage, muscular dystrophy
New Cornell-led research has found a strong connection between DNA damage triggered by mutations in proteins that surround the cell nucleus, known as lamins, and muscular dystrophy. By exploring the mechanisms that cause the damage, the researchers are hopeful their discovery can help shape better treatments. The team’s paper, “Mutant Lamins Cause Nuclear Envelope Rupture...
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Disrupting genetic processes reverses aging in human cells
Research has shed new light on genetic processes that may one day lead to the development of therapies that can slow, or even reverse, how our cells age. A study led by the University of Exeter Medical School has found that certain genes and pathways that regulate splicing factors – a group of proteins in...
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SSB1: Is there a way to delay the aging process, reverse DNA damage, and prevent cancer by restoring a natural protein in the body or turning it off?
To understand what therapeutics could benefit aging and DNA damage, we have to consider what molecules are involved. So, what do we know about this process? There are a number of factors that are involved in the aging process. Many things such as diet, lifestyle, medication, genetics, diseases, amongst countless others, are involved. However, in...
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Potential DNA damage from CRISPR has been ‘seriously underestimated,’ study finds
From the earliest days of the CRISPR-Cas9 era, scientists have known that the first step in how it edits genomes — snipping DNA — creates an unholy mess: Cellular repairmen frantically try to fix the cuts by throwing random chunks of DNA into the breach and deleting other random bits. Research published on Monday suggests that’s only the tip...
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