by Stacey DeLoye, University of Florida An “unbiased” screen for genes involved in opioid tolerance relied upon tiny worms called C. elegans. The worm genetics revealed PTCHD1 plays a key role, altering cholesterol in cell membranes. Credit: Scott Wiseman for UF Scripps Biomedical Research. UF Scripps Biomedical Research scientists have a discovered a key gene that...
Tag: <span>drug tolerance</span>
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Fungal infections: Microbial cooperation leads to drug tolerance
CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN The treatment of fungal infections is often hampered by fungal pathogens that do not respond, or are tolerant, against anti-fungal drugs. A team of researchers from Charité – Universitätsmedizin Berlin and the Francis Crick Institute have now identified microbial cooperation as one of the causes of this drug tolerance. A collaborative...