by University College London A montage of three images of single striatal neurons transfected with a disease-associated version of huntingtin, the protein that causes Huntington’s disease. Nuclei of untransfected neurons are seen in the background (blue). The neuron in the center (yellow) contains an abnormal intracellular accumulation of huntingtin called an inclusion body (orange). Credit:...
Tag: <span>drug trials</span>
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How the Discovery of an Alzheimer’s Tipping Point Could Improve Drug Trials
Researchers have known for many years that Alzheimer’s disease involves two proteins called amyloid-beta and tau, and that interaction drives the spread of neurodegeneration. What hasn’t been clear is where and how those interactions occur over time as the disease progresses. In a study published in the journal Neuron, neurologist William Seeley, MD, and his colleagues at...
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Latin America’s embrace of an unproven COVID treatment is hindering drug trials
Unchecked ivermectin use in the region is making it difficult to test the anti-parasite drug’s effectiveness against the coronavirus. Emiliano Rodríguez Mega Peru (a hospital in Iquitos shown here) has been one of the nations hit hardest by the COVID-19 pandemic. As much of the world waits for an effective vaccine to curb the COVID-19...