by Matt McGowan, University of Arkansas Chemical structure of multi-functional, anticancer drug candidate. Credit: Hassan Beyzavi, University of Arkansas. Researchers at the University of Arkansas have developed a new nano drug candidate that kills triple negative breast cancer cells. Triple negative breast cancer is one of the most aggressive and fatal types of breast cancer....
Tag: <span>Drugs</span>
Single-dose flu drug can reduce spread within households, study finds
UNIVERSITY OF VIRGINIA HEALTH SYSTEM “THIS TRIAL ESTABLISHED THAT BALOXAVIR, IF TAKEN WITHIN A DAY OR SO AFTER EXPOSURE, IS HIGHLY EFFECTIVE FOR PREVENTING INFLUENZA ILLNESS IN HOUSEHOLDS, A HIGH-RISK SETTING FOR VIRUS TRANSMISSION, ” SAID… view more CREDIT: DAN ADDISON | UVA COMMUNICATIONS A single dose of the flu drug baloxavir marboxil can reduce...
How microbiome multi-omics can bolster human health
Sequencing technologies are enabling a deeper analysis of the gut’s microbiome. Researchers can now explore what our microbial inhabitants are doing and how they contribute to, or protect from, disease. investigator of the Human Microbiome Bioactives Resource (HMBR), which provides platforms and methods to integrate 16S sequencing, shotgun metagenomics, metatranscriptomics and meta-metabolomics for microbiome discovery....
HIV pre-exposure drug regimen highly effective in preventing infection
A new drug regimen requiring injections every eight weeks have shown to be more effective in preventing HIV infection than one in which a pill must be taken daily, researchers from the HIV Prevention Trials Network (HPTN) announced at the 23rd International AIDS Conference. Emory University was a key participant in the study, enrolling seven...
Researchers discover first-in-class broad-inhibitor of paramyxovirus polymerases
by Georgia State University A new antiviral drug that is effective against a broad range of human pathogens in the paramyxovirus family, such as the human parainfluenzaviruses and measles virus, has been discovered by researchers in the Institute for Biomedical Sciences at Georgia State University. The drug binds to and inhibits paramyxovirus polymerases, the unique...
Better vaccines are in our blood
by Harvard University Red blood cells do more than shuttle oxygen from our lungs to our organs: they also help the body fight off infections by capturing pathogens on their surfaces, neutralizing them, and presenting them to immune cells in the spleen and liver. Now, a team of researchers from Harvard’s Wyss Institute for Biologically...
Researchers reveal discovery of new cancer drug fadraciclib
by Institute of Cancer Research Scientists have revealed details of the discovery of a new cancer drug that could be used to treat a range of cancer types, including some blood cancers and solid tumors. The drug, called fadraciclib, was jointly discovered by scientists at The Institute of Cancer Research, London, in collaboration with the...
Moffitt researchers find dual inhibitor may be safer for CLL patients
Treatment with the PI3K/ CK1ε inhibitor umbralisib showed fewer immune-mediated adverse reactions compared to PI3K inhibitor therapy H. LEE MOFFITT CANCER CENTER & RESEARCH INSTITUTE TAMPA, Fla. — Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL. Early-stage CLL patients often do not require therapy,...
COVID-19 DRUG MAY CUT DEATH RISK BY 45% FOR SEVERE CASES
In a new study, patients who received single intravenous dose of tocilizumab were also more likely to leave the hospital or be off a ventilator within a month, despite double the risk of additional infection. Critically ill COVID-19 patients who received a single dose of a drug that calms an overreacting immune system were 45%...
Helping drug-delivering particles squeeze through a syringe
MIT engineers are using computing modeling to prevent microparticles from clogging during injections. Microparticles offer a promising way to deliver multiple doses of a drug or vaccine at once because they can be designed to release their payload at specific intervals. However, the particles, which are about the size of a grain of sand, can...