by Alice McCarthy, Harvard Medical School Researchers have found that an existing drug, apilimod, prevented infection of human cells with the SARS-CoV-2 virus. Credit: Tomas Kirchhausen New lab-based studies show that two existing drugs, including one developed by a researcher at Harvard Medical School and Boston Children’s Hospital, inhibit SARS-CoV-2—the virus that causes COVID-19—from infecting...
Tag: <span>Drugs</span>
This revolutionary new coronavirus cure is already saving lives
A breakthrough coronavirus cure might soon be available, as researchers are studying a drug that could eliminate the virus, calm the immune response, and repair damaged tissue. The drug is described in different ways: Medicinal signaling cells (MSCs), mesenchymal lineage adult stem cells, or adipose-tissue derived mesenchymal stromal cells (AT-MSC). MSCs therapy proved to be...
A metabolic enzyme as a potential new target for cancer immune therapies
by German Cancer Research Center The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This was discovered by scientists at the German Cancer Research Center (DKFZ) and the Berlin Institute of Health (BIH). The enzyme that activates the dioxin receptor is produced in large quantities by tumor cells....
Failed Alzheimer’s drugs given new life after human gene discovery
By Rich Haridy August 19, 2020 A new study is questioning whether potential Alzheimer’s treatments previously found to be ineffective in human trials should be re-examined, after the discovery of a specific gene that can inhibit a therapy’s efficacy is only present in 75 percent of people. The long-standing cholinergic hypothesis for Alzheimer’s disease suggests...
The 20 Most Expensive Prescription Drugs in the U.S.A.
Lauren Chase Lauren Chase is on the Research Team at GoodRx. Posted on August 11, 2020 In an effort to continue to shed light on drug prices and increase transparency, the GoodRx Research Team regularly tracks the most expensive drugs in the U.S. Since 2018, we have tracked the list price and dosing requirements to...
FDA Approves Oliceridine, An Intravenous Opioid Severe Acute Pain Relievers for Clinical Use
The United States Food and Drug Administration recently approved Oliceridine, also known as “Olinvyk,” an opioid primarily concerned in treating severe acute pain, by biopharmaceutical company, Trevena, last August 7, 2020. After years of getting the FDA to approve the drug, Trevena, Inc., finally received approval this year. Trevena initially submitted the drug for review...
Lab-created molecule achieves positive results in the treatment of arthritis
Tested in mice with genetically induced arthritis, the substance decreased the area affected, reduced local swelling, and assuaged the pain associated with the inflammatory process. ARTHRITIC MOUSE PAW TREATED WITH TPPU (LEFT) AND UNTREATED PAW OF ANOTHER ARTHRITIC MOUSE. By José Tadeu Arantes | Agência FAPESP – Arthritis affects almost 2% of the world’s population,...
New approach to treating osteoarthritis advances
by NYU Langone Health The study results revolve around the long-established idea that machines within animal and human cells turn the sugars, fats, and proteins we eat into energy used by the body’s millions of cells. The molecule most used to store that energy is called adenosine triphosphate, or ATP. Along with this central role...
Reducing urinary protein for patients with rare kidney disease slows kidney decline
Even without full remission, reducing proteinuria in patients with FSGS allows their kidneys to function longer and extends time to end stage kidney disease CHILDREN’S NATIONAL HOSPITAL Reducing the amount of protein in the urine of patients with focal segmental glomerulosclerosis (FSGS), a rare disease in which scar tissue forms on the parts of the...
U of T researchers discover how to get more cancer-fighting nanoparticles to where they’re needed
Researchers in the University of Toronto’s Faculty of Applied Science & Engineering have discovered a dose threshold that greatly increases the delivery of cancer-fighting drugs into a tumour. The findings, published recently in the journal Nature Materials, provide a potentially universal method for gauging nanoparticle dosage and could help advance a new generation of cancer...