Sarecycline, a drug approved for use in the United States in 2018, is the first new antibiotic approved to treat acne in more than 40 years. Now, researchers at Yale and the University of Illinois-Chicago have discovered how its unique chemical structure makes it effective. Their new study is the most detailed biological analysis to...
Tag: <span>Drugs</span>
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Nasal spray approved for treating suicidal people
by Cynthia Koons Johnson & Johnson’s Spravato has been approved as the first antidepressant for actively suicidal people, as doctors are becoming increasingly concerned about COVID-19’s effect on the mental health of Americans. The Food and Drug Administration approval means the quick-acting nasal spray will be available to people with suicidal thoughts and a plan...
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Tool could improve success in translating drugs from animal studies to humans
by Kayla Wiles, Purdue University Doug Brubaker, a Purdue assistant professor of biomedical engineering, uses computational and experimental approaches to study host-microbiome interactions in cancers and inflammatory diseases. Credit: Purdue University /John Underwood About 50% of people who take the drug infliximab for inflammatory bowel diseases, such as Crohn’s disease, end up becoming resistant or...
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Scientists accelerate progress in preventing drug resistance in lung and pancreas cancers
by Huntsman Cancer Institute Scientists at Huntsman Cancer Institute at the University of Utah report today the development of new models to study molecular characteristics of tumors of the lung and pancreas that are driven by mutations in a gene named NTRK1. The findings were published today in the journal Cell Reports. Credit: Huntsman Cancer...
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Scientists discover that a normal DNA repair process can become a major source of mutations in cancer
by Institute for Research in Biomedicine – IRB Hypermutation is an unusual occurence that can lead to many nearby mutations at once, severely damaging our genetic material and potentially causing cancer. The best known type of local hypermutation, called a mutation shower or thunderstorm, is quite uncommon and it leads to many mutations accumulated in...
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Diabetes drugs could be used to treat multiple sclerosis
Multiple sclerosis (MS) is a debilitating demyelinating disease. It happens when the insulating covers of nerve cells in the brain and spinal cord are damaged and signal transmission in the nervous system becomes disrupted. Scientists at the University of Edinburgh found a way how the body could protect itself from the damages of MS. This...
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Bone drug may be beneficial for knee osteoarthritis
New study highlights the importance and potential promise of targeting structures other than cartilage pathology for the treatment of osteoarthritis BOSTON UNIVERSITY SCHOOL OF MEDICINE (Boston)– Bisphosphonates (a class of drugs that prevent the loss of bone density and used to treat osteoporosis and similar diseases) appear to be safe and beneficial for osteoarthritis patients....
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Beat type 2 diabetes in middle age – and you could fight off Alzheimer’s: Compelling new evidence shows high blood sugar in your 40s may trigger dementia
Study of people with Alzheimer’s found 81 per cent had diabetes or prediabetes Research found cheap diabetes drugs may be able to slow progress of disease The link between diabetes and Alzheimer’s was found by studying brain cells Prof Wharton said insulin resistance could be ‘targeted to improve brain health’ By JO MCFARLANE FOR THE...
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Drug-induced interstitial lung disease in breast cancer patients
A lesson we should learn from multi-disciplinary integration Announcing a new article publication for BIO Integration journal. In this case report the authors Zijun Zhao, Zhanghai He, Hongyan Huang, Jiewen Chen, Shishi He, Ailifeire Yilihamu and Yan Nie from Sun Yat-sen University, Guangzhou, China consider drug-induced interstitial lung disease in breast cancer patients. Taxanes represented...
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Vagus Nerve Stimulator Gets FDA Emergency OK for Asthmatics with COVID
MEDGADGET EDITORS People stricken with COVID-19 exhibit a wide range of symptoms. Some are barely affected while others suffer dire consequences. People with asthma are in particular danger, as SARS-CoV-2 is a respiratory virus that can make breathing even more difficult. Now, the FDA has issued an Emergency Use Authorization for the gammaCore Sapphire CV...