Tag: <span>Drugs</span>

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A never-before-seen cell state may explain cancer’s ability to resist drugs

Cancer’s knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back. Scientists once thought that unique genetic mutations in tumors underlay this drug resistance. But more and more, they are casting their eyes on...

The immune system: Knocked off balance
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The immune system: Knocked off balance

by Ludwig Maximilian University of Munich The immune system: Knocked off balanceInstead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune diseases and allergies. An LMU team has dissected how mast cells regulate their calcium levels to keep the immune response under control. Credit: IMCES UK Essen/LMU Instead...

New bioink for cell bioprinting in 3D
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New bioink for cell bioprinting in 3D

A research group led by Daniel Aili, associate professor at LiU, has developed a bioink to print tissue-mimicking material in 3D printers. The scientists have developed a method and a material that allow cells to survive and thrive. “Bioprinting is a new and exciting technology to manufacture three-dimensional tissue-mimicking cell cultures. It has been a...

Brain tumors may originate in a brain region distinct from where it becomes a lethal disease
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Brain tumors may originate in a brain region distinct from where it becomes a lethal disease

by Children’s National Hospital A mouse model of glioblastoma, an aggressive type of cancer that can occur in the brain, suggests that this recalcitrant cancer originates from a pool of stem cells that can be a significant distance away from the resulting tumors. The findings of a new study, led by Children’s National Hospital researchers...

Researchers identify possible drug target for prostate cancer
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Researchers identify possible drug target for prostate cancer

by Boston University School of Medicine Researchers from Boston University School of Medicine (BUSM) have discovered that the protein BRD4 could be an important new target to prevent castration-resistant prostate cancer metastases. Castration-resistant prostate cancer is a highly aggressive form of prostate cancer that often leads to the development of lethal metastases that kills more...

Scientists identify a new drug target for dry age-related macular degeneration
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Scientists identify a new drug target for dry age-related macular degeneration

by Sanford Burnham Prebys Medical Discovery Institute Francesca Marassi, Ph.D., director of the Cancer, Molecules and Structures Program at Sanford Burnham Prebys Medical Discovery Institute and senior author of the study Credit: Sanford Burnham Prebys Medical Discovery Institute Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that the blood protein vitronectin is a...

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Exhaled biomarkers can reveal lung disease

Specialized nanoparticles create a ‘breath signal’ that could be used to diagnose pneumonia and other infectious or genetic diseases MASSACHUSETTS INSTITUTE OF TECHNOLOGY CAMBRIDGE, MA — Using specialized nanoparticles, MIT engineers have developed a way to monitor pneumonia or other lung diseases by analyzing the breath exhaled by the patient. In a study of mice,...