by UT Southwestern Medical Center The mammalian cannabinoid receptors (CB1 and CB2) sense endogenous endocannabinoids and plant and synthetic cannabinoids to engender a response in the host that leads to decreased inflammation, intestinal motility and secretion, and increased appetite. Mammalian endocannabinoids are also sensed by a bacterial cannabinoid receptor to decrease virulence of enteric pathogens. Endocannabinoids,...
by Leiden University The endogenous compound anandamide—often referred to as the body’s own marijuana—plays a role in erasing memories of a traumatic event. This was discovered by an international team led by Leiden chemist Mario van der Stelt. The results have been published in Nature Chemical Biology and may provide a starting point for the...
Reports from cannabis users that the drug reduces the symptoms of inflammatory bowel disease (IBD) may finally be explained by new research from the University of Massachusetts Medical School and the University of Bath showing that endocannabinoids help control and prevent intestinal inflammation in mice. Credit: CC0 Public Domain This is the first-time scientists have...
