by University of Tsukuba Credit: vitstudio/Shutterstock Anyone who has ever gotten stuck in a traffic jam can attest to the disruption that it causes to your day. Now, researchers from Japan have found that an autism-associated mutation can cause a traffic jam of unfolded proteins that disrupts normal brain function. In a study that was recently...
New study sheds light on how nutrient-starved cells recycle internal components. The idea of the cell as a city is a common introduction to biology, conjuring depictions of the cell’s organelles as power plants, factories, roads, libraries, warehouses and more. Like a city, these structures require a great deal of resources to build and operate,...
by Baylor College of Medicine Batten disease is a family of 13 rare, genetically distinct conditions. Collectively, they are the most prevalent cause of neurodegenerative disease in children, affecting 1 in 12,500 live births in the U.S. One of the Batten disease genes is CLN6. How mutations in this gene lead to the disease has...
Researchers from Kanazawa University identify SLC35B1 as the UDP-glucuronic acid transporter into endoplasmic reticulum. This discovery suggests that SLC35B1 is a key modulator of detoxification process of drugs in the human liver. KANAZAWA UNIVERSITY Kanazawa, Japan – One of the main functions of the liver is to detoxify compounds including drugs and toxicants to reduce...
Like a successful business networker, a cell’s endoplasmic reticulum (ER) is the structure that reaches out—quite literally—to form connections with many different parts of a cell. In several important ways, the ER enables those other parts, or organelles, to do their jobs. Exciting new images of this key member of the cellular workforce may clarify...
Like a successful business networker, a cell’s endoplasmic reticulum (ER) is the structure that reaches out—quite literally—to form connections with many different parts of a cell. In several important ways, the ER enables those other parts, or organelles, to do their jobs. Exciting new images of this key member of the cellular workforce may clarify...
Like a successful business networker, a cell’s endoplasmic reticulum (ER) is the structure that reaches out—quite literally—to form connections with many different parts of a cell. In several important ways, the ER enables those other parts, or organelles, to do their jobs. Exciting new images of this key member of the cellular workforce may clarify...
