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Study uncovers role of mitochondrial energy production in dopaminergic neurons
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Study uncovers role of mitochondrial energy production in dopaminergic neurons

by Melissa Rohman, Northwestern University Ca2+ entry through Cav1 Ca2+ channels triggered ER Ca2+ release. (A) Representative reconstruction of a Fura-2–filled SNc dopaminergic neuron (scale bar, 20 μm). (B) Representative whole-cell current clamp recordings (top) and 2PLSM traces of cytosolic Ca2+ oscillations (bottom) in SNc neurons loaded with Fura-2, before and after application of RYR antagonist DHBP. (C and...