by Sara Lajeunesse, Pennsylvania State University L-type calcium channel blockers (LCCBs)—the most widely used drugs for treating hypertension—may harm the heart as much as help it, according to a new study. The research team, led by Penn State, found that in rats and human cells in vitro, LCCBs cause changes in blood vessels—known as vascular...
Tag: <span>epidemiological</span>
Promising treatment to slow kidney disease doesn’t prove out in clinical trial
Scientists find that reducing levels of uric acid in the blood does not guard against complication in type 1 diabetes. JOSLIN DIABETES CENTER BOSTON – (June 25, 2020) – Historically, half or more of people with type 1 diabetes develop kidney disease, which frequently progresses to kidney failure requiring hemodialysis or a kidney transplant for...
Systemic lupus erythematosus (SLE)
New data show advantage of add-on therapy with belimumab in lupus nephritis Systemic lupus erythematosus (SLE) is a chronic, inflammatory, autoimmune disease, in which damage is caused to multiple organs and tissues by the formation and deposition of immune complexes (antigen-antibody complexes). The kidneys are also affected in about half of the patients when immune...
Glioblastoma Pathway Signatures, Treatment Responses Differ Between Male, Female Patients
NEW YORK (GenomeWeb) – A team led by researchers at Washington University has identified molecular features that differ between glioblastoma (GBM) brain tumors of males and females and may be used to better tailor treatment. As they reported online yesterday in Science Translational Medicine, the researchers used available transcriptome data from the Cancer Genome Atlas...