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Gene variants linked to cerebral arachnoid cysts overlap with developmental disorders, autism, and epilepsy
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Gene variants linked to cerebral arachnoid cysts overlap with developmental disorders, autism, and epilepsy

by Justin Jackson, Medical Xpress Graphical summary of the methodological framework of the study. Credit: Nature Medicine (2023). DOI: 10.1038/s41591-023-02238-2 The most common type of brain cyst (arachnoid) has no known cause. New research investigating patients with these cysts has found something unexpected—a potential genetic link. A team led by Yale University School of Medicine has gathered health history and exome...

Is RNS an effective treatment for epilepsy?
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Is RNS an effective treatment for epilepsy?

Responsive neurostimulation (RNS) is a treatment option that may help to reduce the frequency of seizures. While it does not cure the condition, it is a generally safe, effective, and reversible option to help manage epilepsy. Epilepsy is a common brain condition that can result in seizures. There are various different types of epilepsy that individuals can experience, as...

How the brain’s immune system worsens epilepsy
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How the brain’s immune system worsens epilepsy

by Richard C. Lewis, University of Iowa University of Iowa biologists have definitively linked the brain’s immune system to epilepsy. The caption shows the sequence of events that triggers worsened seizures in fruit flies, which follow a similar pattern in humans. The findings could lead to more effective drugs to treat epilepsy. Credit: John Manak...

Study identifies neuronal basis of impaired consciousness in ‘absence’ epilepsy
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Study identifies neuronal basis of impaired consciousness in ‘absence’ epilepsy

by Yale University BOLD fMRI signals associated with SWDs in GAERS resemble human absence epilepsy. a Statistical Parametric Mapping (SPM) analysis of spike-wave discharge (SWD)-associated changes in blood-oxygen-level-dependent (BOLD) signal. Cortex shows mainly functional magnetic resonance imaging (fMRI) decreases (cool colors), whereas the thalamus shows fMRI increases (warm colors). Values on both color scales indicate the magnitude...

New findings on memory impairment in epilepsy
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New findings on memory impairment in epilepsy

UNIVERSITY OF BONN IMAGE: PLACE CELL OF THE MOUSE: THE DENDRITES ARE EASILY RECOGNIZABLE THANKS TO THE BLUE FLUORESCENCE STAINING. THIS IS WHERE LOCATION INFORMATION IS INTEGRATED. CREDIT: © DR. NICOLA MASALA / UNIVERSITY OF BONN Suppose you go to visit an acquaintance you have not been to see in a long time. Nevertheless, you...

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‘Striking’ Rate of Suicidal Thoughts, Behavior in Teens With Epilepsy

December 07, 2022 NASHVILLE, Tennessee ― About 21% of teens newly diagnosed with epilepsy experience suicidal ideation, and the percentage jumps to 31% within 3 years, new research reveals. Dr Hadley Greenwood “We hope these results inspire epileptologists and neurologists to both recognize and screen for suicide ideation and behaviors in their adolescent patients,” study investigator Hadley Greenwood, third-year...

How can we meet the needs of older adults with epilepsy?
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How can we meet the needs of older adults with epilepsy?

by Monash University Types of studies included in this review. RCT, randomized controlled trial. Credit: Epilepsia (2022). DOI: 10.1111/epi.17426 Older age is now the most common time to develop epilepsy in high-income settings, and an evidence review led by a Monash research team has highlighted that older adults are at risk of new-onset seizures due to age-related...

Genetic testing for epilepsy improves patient outcomes
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Genetic testing for epilepsy improves patient outcomes

by Olivia Dimmer, Northwestern University Reported Clinical Actions After a Definitive Genetic Diagnosis A, Respondents reported whether the genetic finding influenced a change in clinical management of the patient. B, Those who indicated “yes” selected all of the changes that were implemented or recommended (a patient could have >1 recommendation reported and is counted in...

Do people who undergo bariatric surgery have a higher risk of epilepsy?
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Do people who undergo bariatric surgery have a higher risk of epilepsy?

by  American Academy of Neurology Credit: Pixabay/CC0 Public Domain People who have had bariatric surgery may have an increased risk of developing epilepsy, according to a study published in the September 28, 2022, online issue of Neurology. “Bariatric surgery, which involves altering your digestive system, has become a more common treatment for weight loss,” said study author...

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Abortion Ban May Mean Denial of Effective Drugs for Women with MS, Migraine, Epilepsy

The dissolution of Roe v. Wade is expected to lead to abortion bans or severe restrictions in as many as 28 states. These new restrictions may have life-changing and even life-threatening consequences in these states for women of childbearing age with conditions like migraine, multiple sclerosis (MS) and epilepsy. In their perspective article, published in JAMA Neurology,...