Preclinical study shows long-term suppression of seizures CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN Teams of researchers from Charité – Universitätsmedizin Berlin and the Medical University of Innsbruck have developed a new therapeutic concept for the treatment of temporal lobe epilepsy. It represents a gene therapy capable of suppressing seizures at their site of origin on demand. Having...
Tag: <span>epilepsy</span>
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New therapeutic strategy may help reverse autism behavioral abnormalities
by Baylor College of Medicine Autism is a developmental disorder that affects 1 in 59 children in the U.S. Mutations in specific genes, such as PTEN, can explain many autism cases. While children with mutations in PTEN exhibit autism, macrocephaly (an abnormally large skull), intellectual disability and epilepsy, there are currently no effective treatment options...
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Enhancing the way epilepsy is managed by engaging community pharmacists
by University of Washington The University of Washington’s School of Pharmacy announced on Thursday, Sept. 12, a collaboration with global biopharmaceutical company UCB to improve access to care for people living with epilepsy. This interdisciplinary project will explore ways in which community pharmacists can better support people living with this neurological disorder. The roughly 3.4...
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Epilepsy and Epileptogenesis
The term “epilepsy” takes its origin from the Greek verb έπιλαµβάνειν, or epilambánein, which means “to be taken hold of”, “to be seized” or “to be attacked”. Hippocrates (400 BC) was the first to propose that epilepsy is a brain disorder that should be treated. WHO reports that 60 million people around the world suffer from epilepsy and a projected...
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Do neurocysticercosis-related seizures lead to epilepsy?
by The City University of New York Neurocysticercosis, an infection of the brain with pork tapeworm larvae, is highly endemic in Sub-Saharan Africa, Latin America, and Asia, and increasingly common in developed countries like the U.S. due to immigration. The larvae form cysts in the brain, which can cause a variety of neurological symptoms, seizures...
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DNA sequencing study suggests common genetic basis for epilepsy
by Abbey Bigler, Broad Institute of MIT and Harvard Epilepsy is one of the most widespread neurological disorders, but relatively little is known about the genes involved in the more common types. By examining all the genes of over 17,000 people, an international research group has found that more and less severe forms of epilepsy may...
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Cannabidiol-derived drugs and genetic testing provide hope for ‘intractable’ epilepsy in children
by Isabel Derera, The Conversation It can start with a vacant stare, what appear to be muscle twitches or a full-blown seizure. But no matter how it begins, any time a child is diagnosed with epilepsy is often a frightening time for families. About 470,000 children are living with epilepsy in the U.S. While there are over a...
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Cannabis dosage studied at USask to reduce seizures in children with severe epilepsy
Posted Today Children with severe epilepsy also experienced improvements in their quality of life after taking low doses of the medicinal cannabis oil, according to research published in Frontiers in Neurology. The study tested the effects of medicinal cannabis oil with 95 per cent CBD, a chemical which does not create a high, and five percent THC,...
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Can Stem Cells be Used to Treat Epilepsy?
By Osman Shabir, M.Sc. Reviewed by Dr. Jennifer Logan, MD, MPH Epilepsy is a neurological condition characterized by recurrent episodes of seizures. Most cases of epilepsy do not have a clear known cause, apart from susceptible genetic factors. The primary pathogenesis of genetic forms of epilepsy is an abnormal expression of certain receptors in the brain that lead to...
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Epilepsy treatment can cost $5 a year. Millions don’t get it
Think of epilepsy as an electrical storm in the brain. This abnormal brain activity causes seizures, unusual behavior or sensations, or a loss of awareness. Most of the 50 million people who have it can live seizure-free if they take inexpensive, effective medicines. But 80% of people with epilepsy live in low- and middle-income countries,...