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An existing drug may change tumor-associated macrophages back to cancer fighters
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An existing drug may change tumor-associated macrophages back to cancer fighters

by  Jeff Hansen,  University of Alabama at Birmingham Credit: Unsplash/CC0 Public Domain A form of cell communication called hedgehog signaling is vital for embryonic development in mammals. But aberrantly activated hedgehog signaling in multiple cancer types—including breast cancer—promotes tumor invasion, its spread to other organs, and multi-drug resistance. Two years ago, Lalita Shevde, Ph.D., and colleagues...

Existing drug is shown to inhibit SARS-CoV-2 virus
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Existing drug is shown to inhibit SARS-CoV-2 virus

by Emily Ayshford,  University of Chicago Creative rendition of SARS-CoV-2 particles (not to scale). Credit: National Institute of Allergy and Infectious Diseases, NIH A new University of Chicago study has found that the drug masitinib may be effective in treating COVID-19. The drug, which has undergone several clinical trials for human conditions but has not yet...