Researchers hope someday to be able to tell fat cells to burn off excess calories as heat, instead of storing them and causing people to become overweight or obese. REUTERS/Finbarr O’Reilly. Understanding of fat cells could lead to calorie-burning treatments Researchers are a step closer to figuring out how to instruct fat cells to burn off excess...
by Lindsey Tanner This photo provided by Amy Watson of Portland, Ore., shows her during an iron infusion in December 2022. Watson, approaching 50, says she has “never had any kind of recovery” from COVID-19. She has had severe migraines, plus digestive, nerve and foot problems. Recently she developed severe anemia. Credit: Amy Watson via...
UNIVERSITY OF MICHIGAN The findings offer a proof-of-concept for developing therapies against hepatocellular carcinoma, the most common form of liver cancer. Jiandie Lin and his team use mice as a model to study how molecular and cellular changes are affected by nonalcoholic fatty liver disease, and how these changes consequently lead to the progression of this...
by University of California – San Diego Microscopic image of an inflamed pimple with cathelicidin stained red, fat cells stained green and the nuclei of every cell stained blue. Because cathelicidin is produced from fat cells, their staining merges together. Credit: UC San Diego Health Sciences Acne is among the most common skin diseases in...
by Karolinska Institutet Fig. 1: Obesity is associated with altered phosphocreatine/creatine metabolism in human WAT. a, Polar metabolites in subcutaneous WAT of obese (n = 13) and non-obese (NO, n = 13) subjects (cohort 1) highlighting metabolites in the phosphocreatine/creatine pathway (green dots). Data are represented in a volcano plot with fold changes (log2) and adjusted P values (negative...
Fat—it is vital for life but too much can lead to a host of health problems. Studying how fat, or adipose, tissue functions in the body is critical for understanding obesity and other issues, yet structural differences in fat cells and their distribution throughout the body make doing so challenging. “Fat cells are different from...
by UT Southwestern Medical Center Lavanya Vishvanath, Senior Research Associate and Rana Gupta, Ph.D. in the research lab. Credit: UT Southwestern Medical Center A team of researchers at UT Southwestern Medical Center’s Touchstone Diabetes Center have successfully used CRISPR gene editing to turn fat cells normally used for storage into energy-burning cells. “It’s like flipping a switch. We removed the ‘brake’ on...
by Weill Cornell Medical College Credit: Pixabay/CC0 Public Domain COVID-19 may bring high risks of severe disease and death in many patients by disrupting key metabolic signals and thereby triggering hyperglycemia, according to a new study from researchers at Weill Cornell Medicine and NewYork-Presbyterian. In the study, reported Sept. 15 in Cell Metabolism, the researchers found that hyperglycemia—having high blood sugar levels—is common in hospitalized COVID-19 patients and is strongly associated with worse outcomes. The researchers also found evidence suggesting that SARS-CoV-2,...
SHRINERS HOSPITALS FOR CHILDREN IMAGE: LEAD AUTHOR OF THE STUDY, DR. KELSEY COLLINS IS A POSTDOCTORAL FELLOW IN GUILAK’S LABORATORY. CREDIT: SHRINERS HOSPITALS FOR CHILDREN (St. Louis) – A new study by investigators at the Shriners Hospital for Children — St. Louis suggests the damaging effects of obesity are not due to body weight but...
UNIVERSITY OF COPENHAGEN THE FACULTY OF HEALTH AND MEDICAL SCIENCES Why does exercise training make you more fit? It’s well established that exercising enhances insulin sensitivity and improves our metabolism that, in turn, increases exercise performance. But the biological mechanisms underlying this adaptation are not fully understood. New research published in the journal PNAS suggests that part...
