by Johns Hopkins University Credit: Pixabay/CC0 Public Domain In a novel study that identified male chromosome genetic material in the intestines of female patients undergoing fecal transplants, researchers at Johns Hopkins Medicine say they have significantly expanded scientific understanding of how some of these transplants may succeed and work. Fecal microbiota transplant, or FMT, is a...
Tag: <span>Fecal transplant</span>
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COPD improved by tweaks to microbiome via fecal transplant or diet
By Paul McClure COPD symptoms were alleviated by a healthier gut microbiome Depositphotos Improving the health of the gut microbiome by way of fecal transplant (in mice) and dietary modification (in humans), has been shown by researchers to noticeably improve COPD symptoms. The finding could lead to microbiome-targeted treatments that provide relief to people suffering from...
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Clinical trial suggests fecal transplants may protect transplant patients against multi-drug-resistant organisms
by Bob Yirka , Medical Xpress Depth of coverage of metagenome reads from participant stool samples mapped to representative genomes from participants with detected conspecific strain replacement after FMT. (A) Depth of coverage for patients PM01, PM03, PM04, and PM07 show higher coverage depth for replacing strains after FMT. (B) Ratio of coverage depth for...
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Groundbreaking trial of fecal transplant treatment for cancer patients
By Paul McClure March 29, 2023 Researchers in Australia are about to start a pioneering clinical trial using fecal transplantation to treat complications in patients with blood cancers QIMR Berghofer Australia is poised to undertake its first clinical trial using fecal transplantation to treat blood cancer patients who’ve developed serious complications following bone marrow transplantation....
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Fecal transplant throws new light on inflammatory bowel disease
by University of Groningen How the adoptive transfer of altered gut microbiota is sufficient to disrupt/restore intestinal tissue homeostasis. Credit: Markus Schwalbe and Sahar El Aidy, University of Groningen Inflammatory bowel disease is accompanied by a number of changes in the intestines, such as a change in epithelial permeability, a change in the composition of...
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Fecal transplant discovery could improve care for dangerous infections
UNIVERSITY OF VIRGINIA HEALTH SYSTEM New research from the University of Virginia School of Medicine sheds light on why a fecal transplant can benefit patients with dangerous recurrent C. difficile infections – and suggests a way to improve patient outcomes. C. difficile infection causes life-threatening diarrhea, and it often takes hold in patients in hospitals and nursing homes as a...
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Fecal transplant plus fibre supplements improve insulin sensitivity in severely obese patients, clinical trial shows
by University of Alberta A clinical trial led by medicine professor Karen Madsen showed that a single oral fecal transplant followed by fiber supplements improved insulin sensitivity in severely obese patients. Improved insulin sensitivity allows the body to use glucose more effectively, reducing blood sugar. Credit: Photo: Faculty of Medicine & Dentistry A transplant of healthy...
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Fecal transplant turns cancer immunotherapy non-responders into responders
by University of Pittsburgh Credit: CC0 Public Domain Researchers at UPMC Hillman Cancer Center and the National Cancer Institute (NCI) demonstrate that changing the gut microbiome can transform patients with advanced melanoma who never responded to immunotherapy—which has a failure rate of 40% for this type of cancer—into patients who do. The results of this proof-of-principle phase...
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Fecal transplant effective against immunotherapy-induced colitis
For the first time, transplanting gut bacteria from healthy donors was used to successfully treat patients suffering from severe colitis caused by treatment with immune checkpoint inhibitors (ICIs). The study from The University of Texas MD Anderson Cancer Center, which includes two patients, suggests fecal microbiota transplantation (FMT) is worth investigating in clinical trials as...
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Fecal transplant improves autism symptoms
Could the key to helping autistic children lie in their gut? While many people are aware of the behavioural symptoms associated with autism, probably not so many realize that autistics often also have gastrointestinal problems. With that in mind, scientists at the University of Arizona recently conducted a study in which a group of 18...