by Margaret Osborne, Cold Spring Harbor Laboratory Hypothetical read-out mechanisms of the counting neuron. A) This model translates the continuous firing rate of the 1-2-3-many counter neuron into a discrete representation. Because this model uses repetition suppression, larger firing rates correspond to less familiar odors. The counter synapses onto four downstream neurons, each with succcessively...
Researchers identify positive effector behind reduced food intake IMAGE: FRUIT FLIES IN A VIAL IN FRONT OF AMINO ACIDS. CREDIT: MPI F. BIOLOGY OF AGEING/ SEBASTIAN GRÖNKE AND YU-XUAN LU Reduced food intake, known as dietary restriction, leads to a longer lifespan in many animals and can improve health in humans. However, the molecular mechanisms...
Posted Yesterday A triple drug combination has been used to extend the lifespan of fruit flies by 48 percent in a new study led by the Max Planck Institute for Biology of Ageing in Cologne, Germany, and the UCL. The three drugs are all already in use as medical treatments: lithium as a mood stabiliser, trametinib...
Scientists have long known that restricting calories can fend off physiological signs of aging, with studies in fruit flies, roundworms, rodents and even people showing that chronically slashing intake by about a third can reap myriad health benefits and, in some cases, extend lifespan. From a public health perspective, that advice would be impractical for...
