Tag: <span>Gene p16</span>

Home / Gene p16
Gene p16, which drives colorectal cancer, is emerging as a target for potential therapies
Post

Gene p16, which drives colorectal cancer, is emerging as a target for potential therapies

by Homa Shalchi, Baylor College of Medicine Engineered p16 epimutation recapitulates key features of age-associated epigenetic silencing. A p16 DNA methylation profiles in cis-MEF following serial passaging (p). A schematic of the p16 promoter of the cis-element knock-in allele with the CpG maps is shown. B Kinetics of p16 promoter methylation and mRNA expression in ctr-MEF and cis-MEF. Methylation levels were averaged from CpGs from − 814 bp to − 589 bp relative to the TSS....