JANUARY 24, 2022 by Osaka University Fig.1 Reduced contractility and impaired desmosome assembly in isogenic iPS cell-derived cardiomyocytes. (CC BY, © 2022 Hiroyuki Inoue et al., Modeling reduced contractility and impaired desmosome assembly due toplakophilin-2 deficiency using isogenic iPS cell-derived cardiomyocytes. Credit: Stem Cell Reports How can you mend a broken heart? According to researchers from Japan,...
December 23, 2021 | By Liezel Labios SEM image of the “pop-up” sensors that directly measure speed and movement of electrical signals inside heart cells. Credit: Yue Gu Engineers at the University of California San Diego have developed a powerful new tool that monitors the electrical activity inside heart cells, using tiny “pop-up” sensors that poke into cells...
Blocking proton leaks in mitochondria via a transport protein can rejuvenate aging heart cells and helps reverse aging heart dysfunction. Scientists have revealed a mechanism that causes heart cells to age and identified a drug that can rejuvenate them, according to a study published in eLife. The drug is now in clinical trials. The results provide...
A master genetic regulator cardiomyocytes that need to mature may be a clue toward getting heart muscle to regenerate BOSTON CHILDREN’S HOSPITAL Scientists around the world have been trying to replace damaged heart tissue using lab-made heart-muscle cells (cardiomyocytes), either injecting them into the heart or applying patches laced with the cells. But results to date have been underwhelming. IMAGE: A MUTANT HEART MUSCLE CELL (IN GREEN) SURROUNDED...
