Carolyn Brown November 19, 2024 3182 Added to Email Alert A simple, lightweight device worn on the sternum can calculate intracardiac filling pressures, warning that heart failure is worsening, according to a study conducted to determine whether the device can produce the data needed. The developers are designing the CardioTag device to offer advantages over...
Tag: <span>heart failure</span>
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New gene therapy reverses heart failure in large animal model
by University of Utah Health Sciences Fluorescent microscope image of previously failing heart cells that have received cBIN1 gene therapy. Green is a label that indicates the location of cell membranes. The green stripes indicate that the microscopic architecture of heart cells is closer to normal. Credit: Hong lab A new gene therapy can reverse the...
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Researchers engineer experimental drug for preventing heart failure after heart attacks
Posted Today Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have developed a first-of-its-kind experimental therapy that has the potential to enhance heart repair following a heart attack, preventing the onset of heart failure. ENPP1 is expressed in the region of scarring after injury to the heart. Cardiac muscle...
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Exercising with heart failure: Best exercises and tips
by Mike Clark, Rush University Medical Center A cardiac rehab patient exercises on an elliptical training machine at Rush. Credit: Rush University Medical Center We know that exercise is good for our hearts and overall health. But is that true for people living with heart failure? And if it is, how should they start exercising? The...
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Researchers discover how chronic inflammation worsens heart failure
by Sarah C. P. Williams, Gladstone Institutes Stress-activated Cx3cr1+ macrophages contribute to heart failure pathogenesis. Credit: Nature (2024). DOI: 10.1038/s41586-024-08085-6 If you cut your arm or undergo surgery, scarring can be a good thing; the scar tissue produced by cells called fibroblasts helps you heal. In most organs of the body, however, the accumulation of scarring (called fibrosis) is...
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About 6.7 million Americans older than 20 years have heart failure, report suggests
October 3, 2024 by Elana Gotkine About 6.7 million Americans older than age 20 years have heart failure, according to an updated report from the Heart Failure Society of America published online Sept. 24 in the Journal of Cardiac Failure. Biykem Bozkurt, M.D., Ph.D., from the Baylor College of Medicine in Houston, and colleagues updated...
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Heart failure, atrial fibrillation and coronary heart disease linked to cognitive impairment
Credit: Pixabay/CC0 Public Domain Three common cardiovascular diseases in adults—heart failure, atrial fibrillation and coronary heart disease—are linked to cognitive impairment and increased risk of dementia, according to “Cardiac Contributions to Brain Health,” a new scientific statement from the American Heart Association published today in the journal, Stroke. The scientific statement reviews the latest research examining...
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Weight loss drug’s heart benefits extend to people with heart failure
News Release 22-Aug-2024 The anti-obesity medication semaglutide may help to prevent heart attacks and other major adverse cardiac events among overweight people who have cardiovascular disease, whether or not they also have heart failure, according to a new UCL-led study Peer-Reviewed PublicationUniversity College London The anti-obesity medication semaglutide may help to prevent heart attacks and...
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New avenues for treating heart failure: Uncovering a protective mechanism in cardiac myocytes
September 5, 2024 by Tokyo Medical and Dental University Mst1 causes the transport of FoxO1 from the cell cytoplasm to the nucleus by phosphorylating it. This is shown by the colocalization of the green and the blue stain when Ad-Mst1 is added. Credit: Department of Cardiovascular Medicine, TMDUUnderstanding the mechanisms behind cell death and survival...
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Heart failure in type 2 diabetes: Current diagnostic methods unreliable in women
August 5, 2024 by Medical University of Vienna Cumulative survival of male (left) and female (right) patients stratified according to the NYHA classification. Credit: Cardiovascular Diabetology (2024). DOI: 10.1186/s12933-024-02360-6A MedUni Vienna study has investigated gender-specific differences in the diagnosis of systolic heart failure in patients with type 2 diabetes. The results, recently published in the...