by Fraunhofer-Gesellschaft To better understand the molecular signaling pathways in healthy and diseased hearts, researchers are analyzing non-coding miRNA using real-time PCR. This can be used to identify disease-related miRNAs, such as miRNA 132. Credit: Fraunhofer-Gesellschaft RNA has already been making an impact in the context of the vaccine program, but the potential of RNA-based...
by Baylor College of Medicine Credit: Unsplash/CC0 Public Domain Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition. A research team at Baylor College of Medicine and collaborating institutions investigated the function of the protein Rev-erbα/β, a key...
by Ana María Rodríguez, Ph.D., Baylor College of Medicine Using endothelial cell plasticity to improve fibroblast reprograming efficiency. Credit: The authors / Scott Holmes, C.M.I. Not too long ago, the idea of taking—for instance—a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it...
Imagine visiting the doctor, answering a few basic questions, and getting an on-the-spot estimate of whether you’ll experience heart failure in the next 30 years. Such a model now exists, thanks to a new Northwestern Medicine study, which derived and validated the first set of risk prediction models for lifetime risk of heart failure. The ability...
by Northwestern University Credit: Pixabay/CC0 Public Domain Imagine visiting the doctor, answering a few basic questions and getting an on-the-spot estimate of whether you’ll experience heart failure in the next 30 years. Such a model now exists, thanks to a new Northwestern Medicine study, which derived and validated the first set of risk prediction models for lifetime risk of heart...
KAISER PERMANENTE OAKLAND, Calif. — People with HIV are at higher risk of developing heart failure than people without HIV, a new study found. The research, published December 13 in Mayo Clinic Proceedings, is one of the largest studies to investigate heart failure risk in people with HIV and how that risk varies by age, gender, race, and...
by University of East Anglia Credit: Pixabay/CC0 Public Domain A medication originally used for patients with diabetes is the first to help people with heart failure and could revolutionize treatment, according to new research from the University of East Anglia. Early research had shown that Sodium-glucose co-transporter-2 (SGLT2) inhibitors could help around half of heart failure patients—those...
by Melissa Rohman, Northwestern University Effects of dapagliflozin on selected secondary endpoints and in supportive responder analysis. a–c, Effects of dapagliflozin on selected secondary endpoints and in supportive responder analysis. Effects of dapagliflozin versus placebo at 12 weeks on 6MWT distance (a), KCCQ-CS responder analysis (b) and KCCQ-OS (c). Data are presented as mean values with 95%...
(© blueskies9 – stock.adobe.com)HEART HEALTH by Chris Melore SOPHIA ANTIPOLIS, France — Aspirin is one of the most common pain relievers in the world, but a new study finds it may be contributing to heart failure. Researchers with the European Society of Cardiology find taking aspirin raises the risk of heart failure among people with at least...
by American Heart Association Credit: Unsplash/CC0 Public Domain Canagliflozin, a medication used to treat type 2 diabetes, was found to greatly improve symptoms and quality of life within 3 months for people with heart failure due to either reduced or preserved cardiac function, even if they didn’t also have type 2 diabetes, according to late-breaking...
