by Allessandra DiCorato, Broad Institute of MIT and Harvard Fibroblasts, a kind of connective tissue cell in the heart, showing cell nuclei (gray), tubulin (red), and actin (green). Credit: Maria (Masha) Kost-Alimova and Michelle Melanson, Center for the Development of Therapeutics Scientists from the Precision Cardiology Lab (PCL) of the Broad Institute of MIT and...
Tag: <span>heart failure</span>
Researchers identify, test novel drug that may stop heart failure progression
by The Ohio State University Credit: Unsplash/CC0 Public Domain Researchers at The Ohio State University Wexner Medical Center and College of Medicine have developed a novel drug molecule that targets T-cells causing inflammation in heart failure patients, stopping further progression of the disease. During heart failure, T-cells, which are part of the immune system, go from...
Uncontrolled diabetes can advance heart failure from early stage to late stage
JOHNS HOPKINS MEDICINE Among older adults with early stage — also known as preclinical — heart failure, uncontrolled diabetes can substantially increase the risk of heart failure progression, according to a new Johns Hopkins-led study. Researchers found that controlling diabetes early in the heart failure process has immense potential to significantly prevent the progression to...
Long-term study finds cigarette smoking doubled risk of developing heart failure
JOHNS HOPKINS UNIVERSITY BLOOMBERG SCHOOL OF PUBLIC HEALTH A new study from researchers at the Johns Hopkins Bloomberg School of Public Health found that people who smoked tobacco cigarettes developed heart failure at twice the rate of those who never smoked. This higher rate occurred in two major heart failure subtypes and confirms that cigarette...
Speech analysis app predicts worsening heart failure before symptom onset
EUROPEAN SOCIETY OF CARDIOLOGY Madrid, Spain – 21 May 2022: A voice analysis app used by heart failure patients at home recognises fluid in the lungs three weeks before an unplanned hospitalisation or escalation in outpatient drug treatment. The late breaking research is presented at Heart Failure 2022, a scientific congress of the European Society of...
Can AFib cause heart failure?
Atrial fibrillation (AFib) is a condition that causes the heart to beat rapidly and irregularly. This can lead to heart failure, which develops when the heart is not pumping blood efficiently around the body properly. AFib is the most common form of cardiac arrhythmia, meaning it causes an irregular heartbeat. It also causes tachyarrhythmia, which...
Study finds infertility history linked with increased risk of heart failure
by Massachusetts General Hospital Credit: Pixabay/CC0 Public Domain A new study finds that a history of infertility is associated with increased risk of heart failure. Published in the Journal of the American College of Cardiology, researchers from Massachusetts General Hospital (MGH) revealed that women who had experienced infertility had a 16% increased risk of heart failure compared...
Good hydration may reduce long-term risks for heart failure
NIH/NATIONAL HEART, LUNG AND BLOOD INSTITUTE Staying well-hydrated may be associated with a reduced risk for developing heart failure, according to researchers at the National Institutes of Health. Their findings, which appear in the European Heart Journal, suggest that consuming sufficient amounts of fluids throughout life not only supports essential body functioning but may also reduce the risk of severe heart problems in the future. Heart failure, a...
Genetic variation common among Black individuals is associated with higher risk of heart failure and death
by Anna Jones, University of Alabama at Birmingham Credit: Unsplash/CC0 Public Domain A new study published in the Journal of the American Medical Association led by researchers from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine found that being a carrier of a genetic variation known as Val122Ile in the transthyretin, or TTR...
SGLT2 inhibitors reduces hospitalization for heart failure regardless of presence of diabetes
by American College of Physicians Credit: Unsplash/CC0 Public Domain A systematic review and meta-analysis of randomized control trials (RCTs) found that sodium-glucose cotransporter-2 (SGLT2) inhibitors reduce hospitalizations and may reduce cardiovascular deaths among people experiencing heart failure regardless of the presence of diabetes. These findings support existing guidelines that recommend SGLT2 inhibitors for preventing incident...