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Study finds infertility history linked with increased risk of heart failure
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Study finds infertility history linked with increased risk of heart failure

by Massachusetts General Hospital Credit: Pixabay/CC0 Public Domain A new study finds that a history of infertility is associated with increased risk of heart failure. Published in the Journal of the American College of Cardiology, researchers from Massachusetts General Hospital (MGH) revealed that women who had experienced infertility had a 16% increased risk of heart failure compared...

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Good hydration may reduce long-term risks for heart failure

NIH/NATIONAL HEART, LUNG AND BLOOD INSTITUTE Staying well-hydrated may be associated with a reduced risk for developing heart failure, according to researchers at the National Institutes of Health. Their findings, which appear in the European Heart Journal, suggest that consuming sufficient amounts of fluids throughout life not only supports essential body functioning but may also reduce the risk of severe heart problems in the future.   Heart failure, a...

Genetic variation common among Black individuals is associated with higher risk of heart failure and death
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Genetic variation common among Black individuals is associated with higher risk of heart failure and death

by  Anna Jones, University of Alabama at Birmingham Credit: Unsplash/CC0 Public Domain A new study published in the Journal of the American Medical Association led by researchers from the University of Alabama at Birmingham Marnix E. Heersink School of Medicine found that being a carrier of a genetic variation known as Val122Ile in the transthyretin, or TTR...

SGLT2 inhibitors reduces hospitalization for heart failure regardless of presence of diabetes
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SGLT2 inhibitors reduces hospitalization for heart failure regardless of presence of diabetes

by American College of Physicians Credit: Unsplash/CC0 Public Domain A systematic review and meta-analysis of randomized control trials (RCTs) found that sodium-glucose cotransporter-2 (SGLT2) inhibitors reduce hospitalizations and may reduce cardiovascular deaths among people experiencing heart failure regardless of the presence of diabetes. These findings support existing guidelines that recommend SGLT2 inhibitors for preventing incident...

Hold the salt: Study reveals how reducing sodium intake can help patients with heart failure
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Hold the salt: Study reveals how reducing sodium intake can help patients with heart failure

by University of Alberta Credit: Pixabay/CC0 Public Domain For the past century people with weak hearts have been told to lower their salt intake, but until now there has been little scientific evidence behind the recommendation. The largest randomized clinical trial to look at sodium reduction and heart failure reported results simultaneously in The Lancet and at the American College...

Omecamtiv mecarbil does not improve exercise capacity with heart failure
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Omecamtiv mecarbil does not improve exercise capacity with heart failure

by American College of Cardiology Credit: Unsplash/CC0 Public Domain Patients with heart failure with reduced ejection fraction (HFrEF) did not experience any improvement in their ability to exercise vigorously after taking the experimental heart failure drug omecamtiv mecarbil, in a study presented at the American College of Cardiology’s 71st Annual Scientific Session. Many patients who...

FDA expands approval of jardiance for patients with heart failure
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FDA expands approval of jardiance for patients with heart failure

Approval for Jardiance (empagliflozin) has been expanded to reduce the risk for cardiovascular death and hospitalization for heart failure in adults, the U.S. Food and Drug Administration announced Thursday. Jardiance previously received approval in 2014 as a supplement to diet and exercise for improving glucose control in adults with type 2 diabetes. The drug is...

Can correcting micronutrient deficiencies help treat heart failure?
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Can correcting micronutrient deficiencies help treat heart failure?

by Wiley Credit: Pixabay/CC0 Public Domain A review published in the Journal of Internal Medicine provides convincing evidence that micronutrients—including iron, selenium, zinc, copper, and coenzyme Q10—can impact the function of cardiac cells’ energy-producing mitochondria to contribute to heart failure. The findings suggest that micronutrient supplementation could represent an effective treatment for heart failure. “Micronutrient deficiency has...

RNA therapy for heart failure and organ fibrosis
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RNA therapy for heart failure and organ fibrosis

by Fraunhofer-Gesellschaft To better understand the molecular signaling pathways in healthy and diseased hearts, researchers are analyzing non-coding miRNA using real-time PCR. This can be used to identify disease-related miRNAs, such as miRNA 132. Credit: Fraunhofer-Gesellschaft RNA has already been making an impact in the context of the vaccine program, but the potential of RNA-based...