by Stefan Zorn, Medizinische Hochschule Hannover Impending hepatocellular carcinoma diagnosis in cirrhotic patients after HCV cure features a natural killer cell signature. Credit: Hepatology (2024). DOI: 10.1097/HEP.0000000000000804A research team at the MHH is comparing changes in natural killer cells of the innate immune defense system in chronic hepatitis C sufferers as a risk factor for...
by The University of Hong Kong Credit: Pixabay/CC0 Public Domain HKUMed researchers at AIDS Institute, Department of Microbiology and Department of Surgery, School of Clinical Medicine, and School of Biomedical Sciences have discovered the role of an isoformic programmed cell death protein 1 (PD-1), namely Δ42PD-1, in suppressing the function of killer T cells, which...
by University of California, Los Angeles Credit: Pixabay/CC0 Public Domain Primary liver cancer, the third-leading cause of cancer-related death worldwide, takes more than 30,000 lives in the United States each year. The high mortality rates can be attributed in part to the fact that a significant portion of the patients are detected at a late...
DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY SCIENCES IMAGE: IDENTIFICATION AND CHARACTERIZATION OF ROBUST HEPATOCELLULAR CARCINOMA PROGNOSTIC SUBTYPES BASED ON AN INTEGRATIVE METABOLITE-PROTEIN INTERACTION NETWORK CREDIT: DICP A research group led by Prof. PIAO Hailong from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences (CAS) identified hepatocellular carcinoma (HCC) subtypes...
by Perelman School of Medicine at the University of Pennsylvania “Senotherapy,” a treatment that uses small molecule drugs to target “senescent” cells, or those cells that no longer undergo cell division, blunts liver tumor progression in animal models according to new research from a team led by Celeste Simon, Ph.D., a professor of Cell and...
Li-Jie Ma, from Fudan University in Shanghai, and colleagues used telomere-specific fluorescence in situ hybridization and quantitative polymerase chain reaction to assess telomere length in HCC cell lines, tumor tissues, and nontumor cells within the tumor. The researchers found that, compared with their normal counterparts, significant telomere attrition was found in tumor cells and cancer-associated fibroblasts (CAFs), but...
