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Human cocaine and heroin addiction tied to impairments in specific brain circuit initially implicated in animals
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Human cocaine and heroin addiction tied to impairments in specific brain circuit initially implicated in animals

by The Mount Sinai Hospital Structural connections with the prefrontal cortex modeled from targeted nuclei in the subcortex (blue: habenula, yellow: anterior thalamus, red: ventral tegmental area) using diffusion MRI tractography. Microstructural properties of the habenula tract were uniquely reduced in individuals with cocaine or heroin use disorder. Results highlight the potential specificity of distinct...